The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells

The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells

Type 1 diabetes (T1D) is characterized by a prolonged autoimmune attack resulting in the massive loss of insulin-producing beta cells. The initiation and progression of T1D depends on a complex interaction between genetic, immunological and environmental factors. Epidemiological, experimental and cl...

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Main Authors: Maressa Fernandes Bonfim, Camille Aitchedji, Flore Van Goethem, Lionel Sauvage, Thibault Poinsot, Emilie Calonne, Rachel Deplus, François Fuks, Decio L. Eizirik, Anne Op de Beeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Microbiology
Subjects:
m6A
coxsackievirus
pancreatic beta cell
type 1 diabetes
epigenetic regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1501061/full
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