Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy

Cutaneous T-cell lymphoma (CTCL) is a lymphoproliferative disorder of the skin. The most common subtype of CTCL in pediatrics is mycosis fungoides (MF). There are multiple variants of MF. The hypopigmented variant represents more than 50% of MF cases in pediatrics. Misdiagnosis of MF can occur becau...

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Main Authors: Duha Rabi, Balqis Shawer, Ahmad Rabee, Mohammad Qudaimat, Mohammad Milhem, Izzeddin Bakri
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2023/4310796
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author Duha Rabi
Balqis Shawer
Ahmad Rabee
Mohammad Qudaimat
Mohammad Milhem
Izzeddin Bakri
author_facet Duha Rabi
Balqis Shawer
Ahmad Rabee
Mohammad Qudaimat
Mohammad Milhem
Izzeddin Bakri
author_sort Duha Rabi
collection DOAJ
description Cutaneous T-cell lymphoma (CTCL) is a lymphoproliferative disorder of the skin. The most common subtype of CTCL in pediatrics is mycosis fungoides (MF). There are multiple variants of MF. The hypopigmented variant represents more than 50% of MF cases in pediatrics. Misdiagnosis of MF can occur because it may resemble other benign skin pathologies. This is a case of an 11-year-old Palestinian boy presented with generalized nonpruritic hypopigmented maculopapular patches with progressive course for 9-months. Biopsy samples from a hypopigmented patch revealed appearances diagnostic of MF. Immunohistochemical staining was positive for CD3 and CD7 (partial) and a mixture of CD4 and CD8 positive cells. The patient’s case was managed with narrowband ultraviolet B (NBUVB) phototherapy. After a few sessions, the hypopigmented lesions improved significantly.
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issn 2090-6471
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publishDate 2023-01-01
publisher Wiley
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series Case Reports in Dermatological Medicine
spelling doaj-art-667563ecfa8f448eaac139670870a0e42025-02-03T06:12:59ZengWileyCase Reports in Dermatological Medicine2090-64712023-01-01202310.1155/2023/4310796Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian BoyDuha Rabi0Balqis Shawer1Ahmad Rabee2Mohammad Qudaimat3Mohammad Milhem4Izzeddin Bakri5Al Quds UniversityPalestine Polytechnic UniversityPalestine Polytechnic UniversityPalestine Polytechnic UniversityPalestine Polytechnic UniversityMakassed Islamic Charitable HospitalCutaneous T-cell lymphoma (CTCL) is a lymphoproliferative disorder of the skin. The most common subtype of CTCL in pediatrics is mycosis fungoides (MF). There are multiple variants of MF. The hypopigmented variant represents more than 50% of MF cases in pediatrics. Misdiagnosis of MF can occur because it may resemble other benign skin pathologies. This is a case of an 11-year-old Palestinian boy presented with generalized nonpruritic hypopigmented maculopapular patches with progressive course for 9-months. Biopsy samples from a hypopigmented patch revealed appearances diagnostic of MF. Immunohistochemical staining was positive for CD3 and CD7 (partial) and a mixture of CD4 and CD8 positive cells. The patient’s case was managed with narrowband ultraviolet B (NBUVB) phototherapy. After a few sessions, the hypopigmented lesions improved significantly.http://dx.doi.org/10.1155/2023/4310796
spellingShingle Duha Rabi
Balqis Shawer
Ahmad Rabee
Mohammad Qudaimat
Mohammad Milhem
Izzeddin Bakri
Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy
Case Reports in Dermatological Medicine
title Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy
title_full Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy
title_fullStr Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy
title_full_unstemmed Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy
title_short Hypopigmented Mycosis Fungoides in an 11-Year-Old Palestinian Boy
title_sort hypopigmented mycosis fungoides in an 11 year old palestinian boy
url http://dx.doi.org/10.1155/2023/4310796
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AT mohammadqudaimat hypopigmentedmycosisfungoidesinan11yearoldpalestinianboy
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