Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica
The study aimed to investigate the chemical composition and antimicrobial and antioxidant activities of the essential oil from dried seeds of Xylopia aethiopica. The essential oil was obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The essential oil yield was 1.35%. Forty-nine compou...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Biochemistry Research International |
| Online Access: | http://dx.doi.org/10.1155/2024/3923479 |
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| author | Samba Fama Ndoye Yoro Tine Insa Seck Lalla Aicha Ba Seydou Ka Ismaila Ciss Abda Ba Seynabou Sokhna Moussa Ndao Rokhaya Sylla Gueye Nango Gaye Abdoulaye Diop Jean Costa Julien Paolini Matar Seck |
| author_facet | Samba Fama Ndoye Yoro Tine Insa Seck Lalla Aicha Ba Seydou Ka Ismaila Ciss Abda Ba Seynabou Sokhna Moussa Ndao Rokhaya Sylla Gueye Nango Gaye Abdoulaye Diop Jean Costa Julien Paolini Matar Seck |
| author_sort | Samba Fama Ndoye |
| collection | DOAJ |
| description | The study aimed to investigate the chemical composition and antimicrobial and antioxidant activities of the essential oil from dried seeds of Xylopia aethiopica. The essential oil was obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The essential oil yield was 1.35%. Forty-nine compounds were identified in the essential oil with 1,8-cineole (16.3%), β-pinene (14.8%), trans-pinocarveol (9.1%), myrtenol (8.3%), α-pinene (5.9%), and terpinen-4-ol (5.6%) as major components. The antimicrobial activity of this essential oil was studied using disk diffusion and broth microdilution methods on four bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa) and one fungus (Candida albicans). The essential oil exhibited excellent activity against S. aureus, E. faecalis, and C. albicans and moderate activity against E. coli. Among all strains tested, C. albicans showed the best sensitivity with a MIC of 50 mg/mL. The antioxidant activity was examined using a DPPH-free radical scavenging assay. The essential oil of X. aethiopica showed low antioxidant activity (IC50 = 784.604 ± 0.320 mg/mL) compared to that of ascorbic acid and the reference compound (IC50 = 0.163 ± 0.003 mg/mL). The results indicate that consumption of X. aethiopica seeds can reduce the virulence of food-borne pathogens and their resistance to antibiotics. |
| format | Article |
| id | doaj-art-6673e7f6e25f4b93af130d9d3fe490b7 |
| institution | Kabale University |
| issn | 2090-2255 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Biochemistry Research International |
| spelling | doaj-art-6673e7f6e25f4b93af130d9d3fe490b72025-02-03T07:23:43ZengWileyBiochemistry Research International2090-22552024-01-01202410.1155/2024/3923479Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopicaSamba Fama Ndoye0Yoro Tine1Insa Seck2Lalla Aicha Ba3Seydou Ka4Ismaila Ciss5Abda Ba6Seynabou Sokhna7Moussa Ndao8Rokhaya Sylla Gueye9Nango Gaye10Abdoulaye Diop11Jean Costa12Julien Paolini13Matar Seck14Laboratoire de Chimie de Coordination Organique (LCCO)Laboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie de Coordination Organique (LCCO)Université Amadou Mahtar MBOWLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire de Chimie Organique et ThérapeutiqueLaboratoire Bactériologie-VirologieUniversité de CorseUniversité de CorseLaboratoire de Chimie Organique et ThérapeutiqueThe study aimed to investigate the chemical composition and antimicrobial and antioxidant activities of the essential oil from dried seeds of Xylopia aethiopica. The essential oil was obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The essential oil yield was 1.35%. Forty-nine compounds were identified in the essential oil with 1,8-cineole (16.3%), β-pinene (14.8%), trans-pinocarveol (9.1%), myrtenol (8.3%), α-pinene (5.9%), and terpinen-4-ol (5.6%) as major components. The antimicrobial activity of this essential oil was studied using disk diffusion and broth microdilution methods on four bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa) and one fungus (Candida albicans). The essential oil exhibited excellent activity against S. aureus, E. faecalis, and C. albicans and moderate activity against E. coli. Among all strains tested, C. albicans showed the best sensitivity with a MIC of 50 mg/mL. The antioxidant activity was examined using a DPPH-free radical scavenging assay. The essential oil of X. aethiopica showed low antioxidant activity (IC50 = 784.604 ± 0.320 mg/mL) compared to that of ascorbic acid and the reference compound (IC50 = 0.163 ± 0.003 mg/mL). The results indicate that consumption of X. aethiopica seeds can reduce the virulence of food-borne pathogens and their resistance to antibiotics.http://dx.doi.org/10.1155/2024/3923479 |
| spellingShingle | Samba Fama Ndoye Yoro Tine Insa Seck Lalla Aicha Ba Seydou Ka Ismaila Ciss Abda Ba Seynabou Sokhna Moussa Ndao Rokhaya Sylla Gueye Nango Gaye Abdoulaye Diop Jean Costa Julien Paolini Matar Seck Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica Biochemistry Research International |
| title | Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica |
| title_full | Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica |
| title_fullStr | Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica |
| title_full_unstemmed | Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica |
| title_short | Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica |
| title_sort | chemical constituents and antimicrobial and antioxidant activities of essential oil from dried seeds of xylopia aethiopica |
| url | http://dx.doi.org/10.1155/2024/3923479 |
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