Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report
Severe hypertriglyceridemia (SHT) is a rare metabolic complication of diabetic ketoacidosis (DKA) and may complicate the course by leading to acute pancreatitis. While intravenous insulin typically treats the dyslipidemia in these cases, the role of lipid-lowering agents to prevent adverse outcomes...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-09-01
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| Series: | Journal of Pediatric Critical Care |
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| Online Access: | https://journals.lww.com/10.4103/jpcc.jpcc_50_24 |
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| author | Noopur N. Kulkarni Bhakti U. Sarangi Ajay A. Walimbe |
| author_facet | Noopur N. Kulkarni Bhakti U. Sarangi Ajay A. Walimbe |
| author_sort | Noopur N. Kulkarni |
| collection | DOAJ |
| description | Severe hypertriglyceridemia (SHT) is a rare metabolic complication of diabetic ketoacidosis (DKA) and may complicate the course by leading to acute pancreatitis. While intravenous insulin typically treats the dyslipidemia in these cases, the role of lipid-lowering agents to prevent adverse outcomes in patients not responding to insulin warrants further investigation. We report the case of an adolescent girl who presented to us with DKA and SHT (8639 mg/dL), requiring intravenous insulin as well as fibrates. She did not develop any complications that could be attributed to diabetic lipemia; investigations revealed no sequelae of hyperlipidemia or evidence of familial dyslipidemia. |
| format | Article |
| id | doaj-art-666fd11bc6fe4712a2efde81966ff533 |
| institution | Kabale University |
| issn | 2349-6592 2455-7099 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pediatric Critical Care |
| spelling | doaj-art-666fd11bc6fe4712a2efde81966ff5332025-01-23T06:04:17ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992024-09-0111523824010.4103/jpcc.jpcc_50_24Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case reportNoopur N. KulkarniBhakti U. SarangiAjay A. WalimbeSevere hypertriglyceridemia (SHT) is a rare metabolic complication of diabetic ketoacidosis (DKA) and may complicate the course by leading to acute pancreatitis. While intravenous insulin typically treats the dyslipidemia in these cases, the role of lipid-lowering agents to prevent adverse outcomes in patients not responding to insulin warrants further investigation. We report the case of an adolescent girl who presented to us with DKA and SHT (8639 mg/dL), requiring intravenous insulin as well as fibrates. She did not develop any complications that could be attributed to diabetic lipemia; investigations revealed no sequelae of hyperlipidemia or evidence of familial dyslipidemia.https://journals.lww.com/10.4103/jpcc.jpcc_50_24diabetic ketoacidosisdiabetic lipemiasevere hypertriglyceridemia |
| spellingShingle | Noopur N. Kulkarni Bhakti U. Sarangi Ajay A. Walimbe Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report Journal of Pediatric Critical Care diabetic ketoacidosis diabetic lipemia severe hypertriglyceridemia |
| title | Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report |
| title_full | Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report |
| title_fullStr | Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report |
| title_full_unstemmed | Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report |
| title_short | Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report |
| title_sort | severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis a case report |
| topic | diabetic ketoacidosis diabetic lipemia severe hypertriglyceridemia |
| url | https://journals.lww.com/10.4103/jpcc.jpcc_50_24 |
| work_keys_str_mv | AT noopurnkulkarni severehypertriglyceridemiainanadolescentfemalewithdiabeticketoacidosisacasereport AT bhaktiusarangi severehypertriglyceridemiainanadolescentfemalewithdiabeticketoacidosisacasereport AT ajayawalimbe severehypertriglyceridemiainanadolescentfemalewithdiabeticketoacidosisacasereport |