Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study

Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study

BackgroundAlthough immune checkpoint inhibitors (ICIs) and anti-angiogenic drugs have demonstrated effectiveness in treating advanced gastric cancer (GC), their role in neoadjuvant or conversion therapy remains uncertain. This study aimed to evaluate the efficacy and safety of combining neoadjuvant...

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Bibliographic Details
Main Authors: Zhouwei Zhan, Bijuan Chen, Shaohua Xu, Ruyu Lin, Haiting Chen, Xiaohuan Ma, Xuanping Lin, Wanting Huang, Changhua Zhuo, Yu Chen, Zengqing Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
gastric cancer
neoadjuvant treatment
immune checkpoint inhibitors
antiangiogenesis
chemotherapy
survival
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1518217/full
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