Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases

Saved in:
Bibliographic Details
Main Authors: Christopher D. Fage, Munro Passmore, Ben P. Tatman, Helen G. Smith, Xinyun Jian, Upeksha C. Dissanayake, Mia E. Foran, G. Andrés Cisneros, Gregory L. Challis, Józef R. Lewandowski, Matthew Jenner
Format: Article
Language:English
Published: American Chemical Society 2024-11-01
Series:JACS Au
Online Access:https://doi.org/10.1021/jacsau.4c00837
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832584929401110528
author Christopher D. Fage
Munro Passmore
Ben P. Tatman
Helen G. Smith
Xinyun Jian
Upeksha C. Dissanayake
Mia E. Foran
G. Andrés Cisneros
Gregory L. Challis
Józef R. Lewandowski
Matthew Jenner
author_facet Christopher D. Fage
Munro Passmore
Ben P. Tatman
Helen G. Smith
Xinyun Jian
Upeksha C. Dissanayake
Mia E. Foran
G. Andrés Cisneros
Gregory L. Challis
Józef R. Lewandowski
Matthew Jenner
author_sort Christopher D. Fage
collection DOAJ
format Article
id doaj-art-66437954fb434bc6a17f2b006ef127e7
institution Kabale University
issn 2691-3704
language English
publishDate 2024-11-01
publisher American Chemical Society
record_format Article
series JACS Au
spelling doaj-art-66437954fb434bc6a17f2b006ef127e72025-01-27T08:37:20ZengAmerican Chemical SocietyJACS Au2691-37042024-11-015114415710.1021/jacsau.4c00837Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide SynthasesChristopher D. Fage0Munro Passmore1Ben P. Tatman2Helen G. Smith3Xinyun Jian4Upeksha C. Dissanayake5Mia E. Foran6G. Andrés Cisneros7Gregory L. Challis8Józef R. Lewandowski9Matthew Jenner10Department of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, Texas, United StatesDepartment of Chemistry, University of Warwick, Coventry, U.K.Department of Physics, University of Texas at ​Dallas, Richardson, Texas, United StatesDepartment of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry, University of Warwick, Coventry, U.K.Department of Chemistry, University of Warwick, Coventry, U.K.https://doi.org/10.1021/jacsau.4c00837
spellingShingle Christopher D. Fage
Munro Passmore
Ben P. Tatman
Helen G. Smith
Xinyun Jian
Upeksha C. Dissanayake
Mia E. Foran
G. Andrés Cisneros
Gregory L. Challis
Józef R. Lewandowski
Matthew Jenner
Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
JACS Au
title Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
title_full Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
title_fullStr Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
title_full_unstemmed Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
title_short Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases
title_sort molecular basis for short chain thioester hydrolysis by acyl hydrolases in trans acyltransferase polyketide synthases
url https://doi.org/10.1021/jacsau.4c00837
work_keys_str_mv AT christopherdfage molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT munropassmore molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT benptatman molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT helengsmith molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT xinyunjian molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT upekshacdissanayake molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT miaeforan molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT gandrescisneros molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT gregorylchallis molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT jozefrlewandowski molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases
AT matthewjenner molecularbasisforshortchainthioesterhydrolysisbyacylhydrolasesintransacyltransferasepolyketidesynthases