Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population

Squamous cell carcinoma of the skin (SCCs) accounts for 20-30% of non-melanoma skin cancers, resulting in 1 million cases in the United States annually. The risk of developing SCCs increases annually, and this process will likely be continued because of the aging population. We investigated 355 pati...

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Main Authors: Ivelina Yordanova, Preslav Vasilev, Milen Karaivanov, Martin Karamanliev, Dobromir Dimitrov, Petranka Troyanova
Format: Article
Language:English
Published: Medical University - Pleven 2023-12-01
Series:Journal of Biomedical & Clinical Research
Subjects:
Online Access:https://jbcr.arphahub.com/article/34698/download/pdf/
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author Ivelina Yordanova
Preslav Vasilev
Milen Karaivanov
Martin Karamanliev
Dobromir Dimitrov
Petranka Troyanova
author_facet Ivelina Yordanova
Preslav Vasilev
Milen Karaivanov
Martin Karamanliev
Dobromir Dimitrov
Petranka Troyanova
author_sort Ivelina Yordanova
collection DOAJ
description Squamous cell carcinoma of the skin (SCCs) accounts for 20-30% of non-melanoma skin cancers, resulting in 1 million cases in the United States annually. The risk of developing SCCs increases annually, and this process will likely be continued because of the aging population. We investigated 355 patients with histopathologically confirmed SCCs. We rated the age- and sex-related incidence, risk factors, localisation, pathological features, staging systems and treatment, and the recurrence and mortality rates of the tumours. Staging and risk stratification for recurrence and metastases is significant. Most SCCs are successfully treated surgically, with a small subset of carcinomas leading to recurrence, metastasis, and death. Patients with advanced and metastatic disease are often inappropriate for surgical and radiation therapy. We present the first study on squamous cell carcinoma of the skin conducted for the population of the Pleven and Lovech regions of Bulgaria.
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spelling doaj-art-6635d17475044d59a23b62f0db843f8a2025-08-20T02:45:49ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532023-12-0116218018510.2478/jbcr-2023-002434698Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian PopulationIvelina YordanovaPreslav VasilevMilen KaraivanovMartin KaramanlievDobromir DimitrovPetranka TroyanovaSquamous cell carcinoma of the skin (SCCs) accounts for 20-30% of non-melanoma skin cancers, resulting in 1 million cases in the United States annually. The risk of developing SCCs increases annually, and this process will likely be continued because of the aging population. We investigated 355 patients with histopathologically confirmed SCCs. We rated the age- and sex-related incidence, risk factors, localisation, pathological features, staging systems and treatment, and the recurrence and mortality rates of the tumours. Staging and risk stratification for recurrence and metastases is significant. Most SCCs are successfully treated surgically, with a small subset of carcinomas leading to recurrence, metastasis, and death. Patients with advanced and metastatic disease are often inappropriate for surgical and radiation therapy. We present the first study on squamous cell carcinoma of the skin conducted for the population of the Pleven and Lovech regions of Bulgaria.https://jbcr.arphahub.com/article/34698/download/pdf/squamous cell carcinoma of the skinepidemiology
spellingShingle Ivelina Yordanova
Preslav Vasilev
Milen Karaivanov
Martin Karamanliev
Dobromir Dimitrov
Petranka Troyanova
Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population
Journal of Biomedical & Clinical Research
squamous cell carcinoma of the skin
epidemiology
title Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population
title_full Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population
title_fullStr Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population
title_full_unstemmed Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population
title_short Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population
title_sort squamous cell carcinoma of the skin epidemiology diagnosis management recurrence and mortality rates for the bulgarian population
topic squamous cell carcinoma of the skin
epidemiology
url https://jbcr.arphahub.com/article/34698/download/pdf/
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