Aseptic Meningitis Caused by Lassa Virus: Case Series Report
The Lassa virus is known to cause disease in different organ systems of the human body, with varying clinical manifestations. The features of severe clinical disease may include bleeding and/or central nervous system manifestations. Whereas Lassa fever encephalopathy and encephalitis are well descri...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/1978461 |
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| author | Peter O. Okokhere Idowu A. Bankole Christopher O. Iruolagbe Benard E. Muoebonam Martha O. Okonofua Simeon O. Dawodu George O. Akpede |
| author_facet | Peter O. Okokhere Idowu A. Bankole Christopher O. Iruolagbe Benard E. Muoebonam Martha O. Okonofua Simeon O. Dawodu George O. Akpede |
| author_sort | Peter O. Okokhere |
| collection | DOAJ |
| description | The Lassa virus is known to cause disease in different organ systems of the human body, with varying clinical manifestations. The features of severe clinical disease may include bleeding and/or central nervous system manifestations. Whereas Lassa fever encephalopathy and encephalitis are well described in the literature, there is paucity of data on Lassa virus meningitis. We present the clinical description, laboratory diagnosis, and management of 4 consecutive cases of aseptic meningitis associated with Lassa virus infection without bleeding seen in a region of Nigeria known to be endemic for both the reservoir rodent and Lassa fever. The 4 patients recovered fully following intravenous ribavirin treatment and suffered no neurologic complications. |
| format | Article |
| id | doaj-art-66109108c40946d19250a4f2593025fb |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-66109108c40946d19250a4f2593025fb2025-02-03T01:02:36ZengWileyCase Reports in Neurological Medicine2090-66682090-66762016-01-01201610.1155/2016/19784611978461Aseptic Meningitis Caused by Lassa Virus: Case Series ReportPeter O. Okokhere0Idowu A. Bankole1Christopher O. Iruolagbe2Benard E. Muoebonam3Martha O. Okonofua4Simeon O. Dawodu5George O. Akpede6Department of Medicine, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaDepartment of Medicine, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaDepartment of Medicine, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaInstitute of Lassa fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaLassa Fever Ward, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaDepartment of Paediatrics, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaDepartment of Paediatrics, Irrua Specialist Teaching Hospital, Irrua, Edo State, NigeriaThe Lassa virus is known to cause disease in different organ systems of the human body, with varying clinical manifestations. The features of severe clinical disease may include bleeding and/or central nervous system manifestations. Whereas Lassa fever encephalopathy and encephalitis are well described in the literature, there is paucity of data on Lassa virus meningitis. We present the clinical description, laboratory diagnosis, and management of 4 consecutive cases of aseptic meningitis associated with Lassa virus infection without bleeding seen in a region of Nigeria known to be endemic for both the reservoir rodent and Lassa fever. The 4 patients recovered fully following intravenous ribavirin treatment and suffered no neurologic complications.http://dx.doi.org/10.1155/2016/1978461 |
| spellingShingle | Peter O. Okokhere Idowu A. Bankole Christopher O. Iruolagbe Benard E. Muoebonam Martha O. Okonofua Simeon O. Dawodu George O. Akpede Aseptic Meningitis Caused by Lassa Virus: Case Series Report Case Reports in Neurological Medicine |
| title | Aseptic Meningitis Caused by Lassa Virus: Case Series Report |
| title_full | Aseptic Meningitis Caused by Lassa Virus: Case Series Report |
| title_fullStr | Aseptic Meningitis Caused by Lassa Virus: Case Series Report |
| title_full_unstemmed | Aseptic Meningitis Caused by Lassa Virus: Case Series Report |
| title_short | Aseptic Meningitis Caused by Lassa Virus: Case Series Report |
| title_sort | aseptic meningitis caused by lassa virus case series report |
| url | http://dx.doi.org/10.1155/2016/1978461 |
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