Acute electrocardiographic changes during smoking: an observational study
Objective To study the temporal relationship of smoking with electrophysiological changes.Design Prospective observational study.Setting Tertiary cardiac center.Participants Male smokers with atypical chest pain were screened with a treadmill exercise test (TMT). A total of 31 such patients aged 49....
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2013-04-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/3/4/e002486.full |
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| author | Balram Bhargava Sandeep Singh Ambuj Roy Sivasubramanian Ramakrishnan Nitish Naik Kinjal Bhatt Akhilesh K Dubey Sandeep Seth |
| author_facet | Balram Bhargava Sandeep Singh Ambuj Roy Sivasubramanian Ramakrishnan Nitish Naik Kinjal Bhatt Akhilesh K Dubey Sandeep Seth |
| author_sort | Balram Bhargava |
| collection | DOAJ |
| description | Objective To study the temporal relationship of smoking with electrophysiological changes.Design Prospective observational study.Setting Tertiary cardiac center.Participants Male smokers with atypical chest pain were screened with a treadmill exercise test (TMT). A total of 31 such patients aged 49.8±10.5 years, in whom TMT was either negative or mildly positive were included. Heart rate variability (HRV) parameters of smokers were compared to those of 15 healthy non-smoking participants.Interventions All patients underwent a 24 h Holter monitoring to assess ECG changes during smoking periods.Results Heart rate increased acutely during smoking. Mean heart rate increased from 83.8±13.7 bpm 10 min before smoking, to 90.5±16.4 bpm during smoking, (p<0.0001) and returned to baseline after 30 min. Smoking was also associated with increased ectopic beats (mean of 5.3/h prior to smoking to 9.8/h during smoking to 11.3/h during the hour after smoking; p<0.001). Three patients (9.7%) had significant ST–T changes after smoking. HRV index significantly decreased in smokers (15.2±5.3) as compared to non-smoking controls participants (19.4±3.6; p=0.02), but the other spectral HRV parameters were comparable.Conclusions Heart rate and ectopic beats increase acutely following smoking. Ischaemic ST–T changes were also detected during smoking. Spectral parameters of HRV analysis of smokers remained in normal limits, but more importantly geometrical parameter—HRV index—showed significant abnormality. |
| format | Article |
| id | doaj-art-65f38fc7e5ba426aa486ca7c1a326fe9 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2013-04-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-65f38fc7e5ba426aa486ca7c1a326fe92025-02-04T05:45:12ZengBMJ Publishing GroupBMJ Open2044-60552013-04-013410.1136/bmjopen-2012-002486Acute electrocardiographic changes during smoking: an observational studyBalram Bhargava0Sandeep Singh1Ambuj Roy2Sivasubramanian Ramakrishnan3Nitish Naik4Kinjal BhattAkhilesh K DubeySandeep SethIndian Council of Medical Research, New Delhi, IndiaCardiology, Cardio-Thoracic Sciences Centre, All India Institute of Medical Sciences, New Delhi, Delhi, IndiaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, IndiaCardiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, IndiaObjective To study the temporal relationship of smoking with electrophysiological changes.Design Prospective observational study.Setting Tertiary cardiac center.Participants Male smokers with atypical chest pain were screened with a treadmill exercise test (TMT). A total of 31 such patients aged 49.8±10.5 years, in whom TMT was either negative or mildly positive were included. Heart rate variability (HRV) parameters of smokers were compared to those of 15 healthy non-smoking participants.Interventions All patients underwent a 24 h Holter monitoring to assess ECG changes during smoking periods.Results Heart rate increased acutely during smoking. Mean heart rate increased from 83.8±13.7 bpm 10 min before smoking, to 90.5±16.4 bpm during smoking, (p<0.0001) and returned to baseline after 30 min. Smoking was also associated with increased ectopic beats (mean of 5.3/h prior to smoking to 9.8/h during smoking to 11.3/h during the hour after smoking; p<0.001). Three patients (9.7%) had significant ST–T changes after smoking. HRV index significantly decreased in smokers (15.2±5.3) as compared to non-smoking controls participants (19.4±3.6; p=0.02), but the other spectral HRV parameters were comparable.Conclusions Heart rate and ectopic beats increase acutely following smoking. Ischaemic ST–T changes were also detected during smoking. Spectral parameters of HRV analysis of smokers remained in normal limits, but more importantly geometrical parameter—HRV index—showed significant abnormality.https://bmjopen.bmj.com/content/3/4/e002486.full |
| spellingShingle | Balram Bhargava Sandeep Singh Ambuj Roy Sivasubramanian Ramakrishnan Nitish Naik Kinjal Bhatt Akhilesh K Dubey Sandeep Seth Acute electrocardiographic changes during smoking: an observational study BMJ Open |
| title | Acute electrocardiographic changes during smoking: an observational study |
| title_full | Acute electrocardiographic changes during smoking: an observational study |
| title_fullStr | Acute electrocardiographic changes during smoking: an observational study |
| title_full_unstemmed | Acute electrocardiographic changes during smoking: an observational study |
| title_short | Acute electrocardiographic changes during smoking: an observational study |
| title_sort | acute electrocardiographic changes during smoking an observational study |
| url | https://bmjopen.bmj.com/content/3/4/e002486.full |
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