Role of Intracoronary Imaging in Acute Coronary Syndromes

Intravascular imaging with optical coherence tomography (OCT) and intravascular ultrasound provides superior visualization of the culprit plaques for acute coronary syndromes (ACS) compared with coronary angiography. Combined with angiography, intravascular imaging can be used to instigate ‘precisio...

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Main Authors: Gregory Petrossian, Denizhan Ozdemir, Keyvan Karimi Galougahi, Jonathan Scheiner, Susan V Thomas, Richard Shlofmitz, Evan Shlofmitz, Allen Jeremias, Ziad A Ali
Format: Article
Language:English
Published: Radcliffe Medical Media 2022-06-01
Series:US Cardiology Review
Online Access:https://www.uscjournal.com/articleindex/usc.2022.03
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author Gregory Petrossian
Denizhan Ozdemir
Keyvan Karimi Galougahi
Jonathan Scheiner
Susan V Thomas
Richard Shlofmitz
Evan Shlofmitz
Allen Jeremias
Ziad A Ali
author_facet Gregory Petrossian
Denizhan Ozdemir
Keyvan Karimi Galougahi
Jonathan Scheiner
Susan V Thomas
Richard Shlofmitz
Evan Shlofmitz
Allen Jeremias
Ziad A Ali
author_sort Gregory Petrossian
collection DOAJ
description Intravascular imaging with optical coherence tomography (OCT) and intravascular ultrasound provides superior visualization of the culprit plaques for acute coronary syndromes (ACS) compared with coronary angiography. Combined with angiography, intravascular imaging can be used to instigate ‘precision therapy’ for ACS. Post-mortem histopathology identified atherothrombosis at the exposed surface of a ruptured fibrous cap as the main cause of ACS. Further histopathological studies identified intact fibrous caps and calcified nodules as other culprit lesions for ACS. These plaque types were subsequently also identified on intravascular imaging, particularly with the high-resolution OCT. The less-common non-atherothrombotic causes of ACS are coronary artery spasm, coronary artery dissection, and coronary embolism. In this review, the authors provide an overview of clinical studies using intravascular imaging with OCT in the diagnosis and management of ACS.
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publisher Radcliffe Medical Media
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series US Cardiology Review
spelling doaj-art-65e46c7f8f5e4d15801b881738c01ff82025-08-20T01:56:39ZengRadcliffe Medical MediaUS Cardiology Review1758-38961758-390X2022-06-011610.15420/usc.2022.03Role of Intracoronary Imaging in Acute Coronary SyndromesGregory Petrossian0Denizhan Ozdemir1Keyvan Karimi Galougahi2Jonathan Scheiner3Susan V Thomas4Richard Shlofmitz5Evan Shlofmitz6Allen Jeremias7Ziad A Ali8Albany Medical College, Albany Medical Center, Albany, NYDivision of Cardiology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, NYDepartment of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia; Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Heart Research Institute, Sydney, Australia; DeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NYDeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NYDeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NYDeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NYDeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NYDeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NY; Clinical Trials Center, Cardiovascular Research Foundation, New York, NYDeMatteis Cardiovascular Institute, St Francis Hospital – The Heart Center, Roslyn, NY; Clinical Trials Center, Cardiovascular Research Foundation, New York, NYIntravascular imaging with optical coherence tomography (OCT) and intravascular ultrasound provides superior visualization of the culprit plaques for acute coronary syndromes (ACS) compared with coronary angiography. Combined with angiography, intravascular imaging can be used to instigate ‘precision therapy’ for ACS. Post-mortem histopathology identified atherothrombosis at the exposed surface of a ruptured fibrous cap as the main cause of ACS. Further histopathological studies identified intact fibrous caps and calcified nodules as other culprit lesions for ACS. These plaque types were subsequently also identified on intravascular imaging, particularly with the high-resolution OCT. The less-common non-atherothrombotic causes of ACS are coronary artery spasm, coronary artery dissection, and coronary embolism. In this review, the authors provide an overview of clinical studies using intravascular imaging with OCT in the diagnosis and management of ACS.https://www.uscjournal.com/articleindex/usc.2022.03
spellingShingle Gregory Petrossian
Denizhan Ozdemir
Keyvan Karimi Galougahi
Jonathan Scheiner
Susan V Thomas
Richard Shlofmitz
Evan Shlofmitz
Allen Jeremias
Ziad A Ali
Role of Intracoronary Imaging in Acute Coronary Syndromes
US Cardiology Review
title Role of Intracoronary Imaging in Acute Coronary Syndromes
title_full Role of Intracoronary Imaging in Acute Coronary Syndromes
title_fullStr Role of Intracoronary Imaging in Acute Coronary Syndromes
title_full_unstemmed Role of Intracoronary Imaging in Acute Coronary Syndromes
title_short Role of Intracoronary Imaging in Acute Coronary Syndromes
title_sort role of intracoronary imaging in acute coronary syndromes
url https://www.uscjournal.com/articleindex/usc.2022.03
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