Tryptophan Kynurenine Pathway-Based Imaging Agents for Brain Disorders and Oncology—From Bench to Bedside
Tryptophan (Trp)-based radiotracers have excellent potential for imaging many different types of brain pathology because of their involvement with both the serotonergic and kynurenine (KYN) pathways. However, radiotracers specific to the kynurenine metabolism pathway are limited. In addition, histor...
Saved in:
Main Authors: | Erik Stauff, Wenqi Xu, Heidi H. Kecskemethy, Sigrid A. Langhans, Vinay V. R. Kandula, Lauren W. Averill, Xuyi Yue |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-01-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/15/1/47 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Peripheral tryptophan-kynurenine pathway dysfunction in first-episode schizophrenia
by: Mian Li, et al.
Published: (2025-01-01) -
Tryptophan as a biomarker of pregnancy-related immune expression and modulation: an integrative review
by: Stephanie Prescott, et al.
Published: (2025-01-01) -
Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder
by: Ágnes Szabó, et al.
Published: (2025-01-01) -
Targeting the kynurenine pathway: another therapeutic opportunity in the metabolic crosstalk between cancer and immune cells
by: Irene Kang, et al.
Published: (2025-01-01) -
D-tryptophan triggered epithelial-mesenchymal transition by activating TGF-β signaling pathway
by: Chong Wang, et al.
Published: (2022-09-01)