A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature

Kikuchi–Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare disease that is frequently underdiagnosed due to clinical features that are similar to those of non-Hodgkin lymphomas, systemic lupus erythematosus (SLE), or infectious reactive lymphadenopathy. An excisional biopsy is...

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Main Authors: Mihaela Găman, Ana-Maria Vlădăreanu, Camelia Dobrea, Minodora Onisâi, Cristina Marinescu, Irina Voican, Daniela Vasile, Horia Bumbea, Diana Cîşleanu
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2018/1791627
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author Mihaela Găman
Ana-Maria Vlădăreanu
Camelia Dobrea
Minodora Onisâi
Cristina Marinescu
Irina Voican
Daniela Vasile
Horia Bumbea
Diana Cîşleanu
author_facet Mihaela Găman
Ana-Maria Vlădăreanu
Camelia Dobrea
Minodora Onisâi
Cristina Marinescu
Irina Voican
Daniela Vasile
Horia Bumbea
Diana Cîşleanu
author_sort Mihaela Găman
collection DOAJ
description Kikuchi–Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare disease that is frequently underdiagnosed due to clinical features that are similar to those of non-Hodgkin lymphomas, systemic lupus erythematosus (SLE), or infectious reactive lymphadenopathy. An excisional biopsy is required. We report a young Caucasian female diagnosed with KFD with skin lesions, complicating with SLE. The clinical course, laboratory, and CT findings are described, as are histopathologic features, for a better recognition of this rare disorder in clinical practice.
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institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-65d59541d4f947ccbe381c8fd5eb7e6c2025-02-03T05:45:47ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/17916271791627A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the LiteratureMihaela Găman0Ana-Maria Vlădăreanu1Camelia Dobrea2Minodora Onisâi3Cristina Marinescu4Irina Voican5Daniela Vasile6Horia Bumbea7Diana Cîşleanu8Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Hematology, University Emergency Hospital Bucharest, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaKikuchi–Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare disease that is frequently underdiagnosed due to clinical features that are similar to those of non-Hodgkin lymphomas, systemic lupus erythematosus (SLE), or infectious reactive lymphadenopathy. An excisional biopsy is required. We report a young Caucasian female diagnosed with KFD with skin lesions, complicating with SLE. The clinical course, laboratory, and CT findings are described, as are histopathologic features, for a better recognition of this rare disorder in clinical practice.http://dx.doi.org/10.1155/2018/1791627
spellingShingle Mihaela Găman
Ana-Maria Vlădăreanu
Camelia Dobrea
Minodora Onisâi
Cristina Marinescu
Irina Voican
Daniela Vasile
Horia Bumbea
Diana Cîşleanu
A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature
Case Reports in Hematology
title A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature
title_full A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature
title_fullStr A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature
title_full_unstemmed A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature
title_short A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature
title_sort challenging case of kikuchi fujimoto disease associated with systemic lupus erythematosus and review of the literature
url http://dx.doi.org/10.1155/2018/1791627
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