Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient
Necrotizing soft tissue infections are characterized clinically by fulminant tissue destruction, systemic signs of toxicity, and high mortality. Accurate diagnosis and appropriate treatment must include early surgical intervention and antibiotic therapy. Mortality rate is very high and could be even...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2017/3718360 |
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| author | Sudheer Nambiar Asha Karippot Joe Devasahayam Tony Oliver |
| author_facet | Sudheer Nambiar Asha Karippot Joe Devasahayam Tony Oliver |
| author_sort | Sudheer Nambiar |
| collection | DOAJ |
| description | Necrotizing soft tissue infections are characterized clinically by fulminant tissue destruction, systemic signs of toxicity, and high mortality. Accurate diagnosis and appropriate treatment must include early surgical intervention and antibiotic therapy. Mortality rate is very high and could be even higher in an immunocompromised host. We present a 57-year-old female with history of rheumatoid arthritis on oral corticosteroid and methotrexate therapy with painful swelling of the left hand following a cat bite that was diagnosed as having group A streptococcus pyogenes-associated necrotizing fasciitis. Treatment with ampicillin-sulbactam, Clindamycin, and surgical debridement was performed. In spite of all the adequate therapy she succumbed to death from streptococcal toxic shock and related complications after thirty-two days of treatment in intensive care unit. Necrotizing fasciitis is an uncommon but life-threatening complication in immunocompromised hosts. Tissue infections in cat bite wounds are commonly caused by pathogenic bacterium known as Pasteurella multocida. Group A streptococcal infections are not reported following cat bites. A high index of suspicion must be maintained to suspect group A streptococcal associated necrotizing fasciitis following cat bites and an early medical and surgical intervention should be made for any best possible outcome. |
| format | Article |
| id | doaj-art-65a6cdad4bcf49c6bcb92f9fc8b22e92 |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-65a6cdad4bcf49c6bcb92f9fc8b22e922025-02-03T05:47:06ZengWileyCase Reports in Critical Care2090-64202090-64392017-01-01201710.1155/2017/37183603718360Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised PatientSudheer Nambiar0Asha Karippot1Joe Devasahayam2Tony Oliver3Pulmonary Critical Care Medicine, Medical City Denton, Denton, TX, USAHematology and Oncology, Medical City Denton, Denton, TX, USAPulmonary Critical Care Medicine, University of Missouri, Columbia, MO, USAUSD Sanford School of Medicine, Vermillion, SD, USANecrotizing soft tissue infections are characterized clinically by fulminant tissue destruction, systemic signs of toxicity, and high mortality. Accurate diagnosis and appropriate treatment must include early surgical intervention and antibiotic therapy. Mortality rate is very high and could be even higher in an immunocompromised host. We present a 57-year-old female with history of rheumatoid arthritis on oral corticosteroid and methotrexate therapy with painful swelling of the left hand following a cat bite that was diagnosed as having group A streptococcus pyogenes-associated necrotizing fasciitis. Treatment with ampicillin-sulbactam, Clindamycin, and surgical debridement was performed. In spite of all the adequate therapy she succumbed to death from streptococcal toxic shock and related complications after thirty-two days of treatment in intensive care unit. Necrotizing fasciitis is an uncommon but life-threatening complication in immunocompromised hosts. Tissue infections in cat bite wounds are commonly caused by pathogenic bacterium known as Pasteurella multocida. Group A streptococcal infections are not reported following cat bites. A high index of suspicion must be maintained to suspect group A streptococcal associated necrotizing fasciitis following cat bites and an early medical and surgical intervention should be made for any best possible outcome.http://dx.doi.org/10.1155/2017/3718360 |
| spellingShingle | Sudheer Nambiar Asha Karippot Joe Devasahayam Tony Oliver Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient Case Reports in Critical Care |
| title | Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient |
| title_full | Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient |
| title_fullStr | Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient |
| title_full_unstemmed | Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient |
| title_short | Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient |
| title_sort | group a streptococci associated necrotizing fasciitis following cat bite in an immunocompromised patient |
| url | http://dx.doi.org/10.1155/2017/3718360 |
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