Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review

Abstract Liver cancer is one of the most challenging malignancies, often associated with poor prognosis and limited treatment options. Recent advancements in nanotechnology and artificial intelligence (AI) have opened new frontiers in the fight against this disease. Nanotechnology enables precise, t...

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Main Authors: Manjusha Bhange, Darshan Telange
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-01821-y
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author Manjusha Bhange
Darshan Telange
author_facet Manjusha Bhange
Darshan Telange
author_sort Manjusha Bhange
collection DOAJ
description Abstract Liver cancer is one of the most challenging malignancies, often associated with poor prognosis and limited treatment options. Recent advancements in nanotechnology and artificial intelligence (AI) have opened new frontiers in the fight against this disease. Nanotechnology enables precise, targeted drug delivery, enhancing the efficacy of therapeutics while minimizing off-target effects. Simultaneously, AI contributes to improved diagnostic accuracy, predictive modeling, and the development of personalized treatment strategies. This review explores the convergence of nanotechnology and AI in liver cancer treatment, evaluating current progress, identifying existing research gaps, and discussing future directions. We highlight how AI-powered algorithms can optimize nanocarrier design, facilitate real-time monitoring of treatment efficacy, and enhance clinical decision-making. By integrating AI with nanotechnology, clinicians can achieve more accurate patient stratification and treatment personalization, ultimately improving patient outcomes. This convergence holds significant promise for transforming liver cancer therapy into a more precise, individualized, and efficient process. However, data privacy, regulatory hurdles, and the need for large-scale clinical validation remain. Addressing these issues will be essential to fully realizing the potential of these technologies in oncology.
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spelling doaj-art-658c874faa374105b40fbff2c12dab482025-01-26T12:39:50ZengSpringerDiscover Oncology2730-60112025-01-0116112010.1007/s12672-025-01821-yConvergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive reviewManjusha Bhange0Darshan Telange1Department of Pharmaceutics, Datta Meghe College of Pharmacy, Datta Meghe Institute of Higher Education and Research (DU)Department of Pharmaceutics, Datta Meghe College of Pharmacy, Datta Meghe Institute of Higher Education and Research (DU)Abstract Liver cancer is one of the most challenging malignancies, often associated with poor prognosis and limited treatment options. Recent advancements in nanotechnology and artificial intelligence (AI) have opened new frontiers in the fight against this disease. Nanotechnology enables precise, targeted drug delivery, enhancing the efficacy of therapeutics while minimizing off-target effects. Simultaneously, AI contributes to improved diagnostic accuracy, predictive modeling, and the development of personalized treatment strategies. This review explores the convergence of nanotechnology and AI in liver cancer treatment, evaluating current progress, identifying existing research gaps, and discussing future directions. We highlight how AI-powered algorithms can optimize nanocarrier design, facilitate real-time monitoring of treatment efficacy, and enhance clinical decision-making. By integrating AI with nanotechnology, clinicians can achieve more accurate patient stratification and treatment personalization, ultimately improving patient outcomes. This convergence holds significant promise for transforming liver cancer therapy into a more precise, individualized, and efficient process. However, data privacy, regulatory hurdles, and the need for large-scale clinical validation remain. Addressing these issues will be essential to fully realizing the potential of these technologies in oncology.https://doi.org/10.1007/s12672-025-01821-yLiver cancerNanotechnologyArtificial intelligencePersonalized medicine
spellingShingle Manjusha Bhange
Darshan Telange
Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
Discover Oncology
Liver cancer
Nanotechnology
Artificial intelligence
Personalized medicine
title Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
title_full Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
title_fullStr Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
title_full_unstemmed Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
title_short Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
title_sort convergence of nanotechnology and artificial intelligence in the fight against liver cancer a comprehensive review
topic Liver cancer
Nanotechnology
Artificial intelligence
Personalized medicine
url https://doi.org/10.1007/s12672-025-01821-y
work_keys_str_mv AT manjushabhange convergenceofnanotechnologyandartificialintelligenceinthefightagainstlivercanceracomprehensivereview
AT darshantelange convergenceofnanotechnologyandartificialintelligenceinthefightagainstlivercanceracomprehensivereview