Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases
Nanotechnology, particularly through the use of nanocomposites, holds great promise in addressing the challenges of skin diseases, which are often difficult to treat due to the complex anatomy of the skin and limitations of traditional therapies. Nanocomposites, composed of nanoparticles integrated...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Next Nanotechnology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949829525000087 |
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| author | Sandipan Dasgupta Subhasundar Maji Sanjay Dey Moitreyee Chattopadhyay Ananya Chanda Satarupa Acharjee Kousik Santra Kazi Asraf Ali |
| author_facet | Sandipan Dasgupta Subhasundar Maji Sanjay Dey Moitreyee Chattopadhyay Ananya Chanda Satarupa Acharjee Kousik Santra Kazi Asraf Ali |
| author_sort | Sandipan Dasgupta |
| collection | DOAJ |
| description | Nanotechnology, particularly through the use of nanocomposites, holds great promise in addressing the challenges of skin diseases, which are often difficult to treat due to the complex anatomy of the skin and limitations of traditional therapies. Nanocomposites, composed of nanoparticles integrated into matrix materials like polymers, metals, or ceramics, offer enhanced therapeutic efficacy and targeted delivery. Their unique properties enable customized solutions for specific dermatological applications. For example, graphene oxide-based nanocomposites improve penetration of the skin’s stratum corneum, facilitating deeper drug delivery. Silver and curcumin-based nanocomposites provide controlled release of active ingredients over extended periods, protecting bioactive compounds from degradation. Additionally, hydroxyapatite-based nanocomposites enhance mechanical properties and bioactivity through chemical bonding with the polymer matrix. These advancements show significant potential in treating various skin conditions, including wounds, infections, cancer, and tissue engineering. Nanocomposites also excel in antimicrobial therapies, promoting wound healing, combating bacterial and fungal infections, and targeting cancer cells in skin carcinoma treatments. Their ability to improve diagnostic imaging and facilitate tissue regeneration further expands their applications. Despite these promising benefits, concerns about biocompatibility, toxicity, and legal challenges remain, necessitating further research to develop standardized protocols for clinical use. The future of nanocomposites in dermatology looks promising, with innovations in personalized medicine, smart drug delivery, and multifunctional materials driving progress. Continued research and development will be essential to unlock the full potential of nanocomposites in enhancing clinical dermatology. Overall, this review covers the various aspects of nanocomposites for treating of skin diseases and provide a holistic understanding that can guide future research and improve clinical practices in dermatology. |
| format | Article |
| id | doaj-art-658885f4a7f74889a28a24079a01692b |
| institution | Kabale University |
| issn | 2949-8295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Next Nanotechnology |
| spelling | doaj-art-658885f4a7f74889a28a24079a01692b2025-02-02T05:29:38ZengElsevierNext Nanotechnology2949-82952025-01-017100139Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseasesSandipan Dasgupta0Subhasundar Maji1Sanjay Dey2Moitreyee Chattopadhyay3Ananya Chanda4Satarupa Acharjee5Kousik Santra6Kazi Asraf Ali7Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Nadia, West Bengal 741249, IndiaDepartment of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Nadia, West Bengal 741249, IndiaDepartment of Pharmaceutical Technology, School of Health and Medical Sciences, Adamas University, Barasat, Kolkata, West Bengal 700126, IndiaDepartment of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Nadia, West Bengal 741249, IndiaDepartment of Pharmaceutical Technology, School of Health and Medical Sciences, Adamas University, Barasat, Kolkata, West Bengal 700126, IndiaDepartment of Pharmaceutical Technology, NSHM Knowledge Campus, Kolkata Group of Institutions, Kolkata 700053, IndiaDepartment of Pharmaceutical Technology, Anand College of Education, Paschim Medinipur, West Bengal 721126, IndiaDepartment of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Nadia, West Bengal 741249, India; Corresponding author.Nanotechnology, particularly through the use of nanocomposites, holds great promise in addressing the challenges of skin diseases, which are often difficult to treat due to the complex anatomy of the skin and limitations of traditional therapies. Nanocomposites, composed of nanoparticles integrated into matrix materials like polymers, metals, or ceramics, offer enhanced therapeutic efficacy and targeted delivery. Their unique properties enable customized solutions for specific dermatological applications. For example, graphene oxide-based nanocomposites improve penetration of the skin’s stratum corneum, facilitating deeper drug delivery. Silver and curcumin-based nanocomposites provide controlled release of active ingredients over extended periods, protecting bioactive compounds from degradation. Additionally, hydroxyapatite-based nanocomposites enhance mechanical properties and bioactivity through chemical bonding with the polymer matrix. These advancements show significant potential in treating various skin conditions, including wounds, infections, cancer, and tissue engineering. Nanocomposites also excel in antimicrobial therapies, promoting wound healing, combating bacterial and fungal infections, and targeting cancer cells in skin carcinoma treatments. Their ability to improve diagnostic imaging and facilitate tissue regeneration further expands their applications. Despite these promising benefits, concerns about biocompatibility, toxicity, and legal challenges remain, necessitating further research to develop standardized protocols for clinical use. The future of nanocomposites in dermatology looks promising, with innovations in personalized medicine, smart drug delivery, and multifunctional materials driving progress. Continued research and development will be essential to unlock the full potential of nanocomposites in enhancing clinical dermatology. Overall, this review covers the various aspects of nanocomposites for treating of skin diseases and provide a holistic understanding that can guide future research and improve clinical practices in dermatology.http://www.sciencedirect.com/science/article/pii/S2949829525000087NanocompositeSkin diseaseTherapeutic innovationTreatment modalitiesClinical dermatology |
| spellingShingle | Sandipan Dasgupta Subhasundar Maji Sanjay Dey Moitreyee Chattopadhyay Ananya Chanda Satarupa Acharjee Kousik Santra Kazi Asraf Ali Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases Next Nanotechnology Nanocomposite Skin disease Therapeutic innovation Treatment modalities Clinical dermatology |
| title | Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases |
| title_full | Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases |
| title_fullStr | Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases |
| title_full_unstemmed | Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases |
| title_short | Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases |
| title_sort | exploring nanocomposite materials in clinical dermatology innovations for treating skin diseases |
| topic | Nanocomposite Skin disease Therapeutic innovation Treatment modalities Clinical dermatology |
| url | http://www.sciencedirect.com/science/article/pii/S2949829525000087 |
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