Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer

Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer

Background/AimsIt was recently reported that a higher concentration of the bacterially produced metabolite indole 3-acetate (3-IAA) in blood was linked to a better response to chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma (PDAC). Here, we aimed to extend these observation...

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Bibliographic Details
Main Authors: Peder R. Braadland, Ingvild Farnes, Elin H. Kure, Sheraz Yaqub, Adrian McCann, Per M. Ueland, Knut Jørgen Labori, Johannes R. Hov
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Oncology
Subjects:
pancreatic adenocarcinoma
chemotherapy - oncology
biomarkers
microbiome
indoles
3-IAA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1488749/full
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