Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis
Disseminated toxoplasmosis is uncommon in both immunocompetent and immunocompromised hosts with gastrointestinal involvement being rarely described. We report a case of disseminated gastrointestinal toxoplasmosis in an immunocompromised man who presented with one month of diarrhea and abdominal pain...
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Format: | Article |
Language: | English |
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Wiley
2017-01-01
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Series: | Case Reports in Gastrointestinal Medicine |
Online Access: | http://dx.doi.org/10.1155/2017/3491087 |
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author | Matthew Glover Zhouwen Tang Robert Sealock Shilpa Jain |
author_facet | Matthew Glover Zhouwen Tang Robert Sealock Shilpa Jain |
author_sort | Matthew Glover |
collection | DOAJ |
description | Disseminated toxoplasmosis is uncommon in both immunocompetent and immunocompromised hosts with gastrointestinal involvement being rarely described. We report a case of disseminated gastrointestinal toxoplasmosis in an immunocompromised man who presented with one month of diarrhea and abdominal pain. Imaging showed thickening of the ascending colon and cecum. Esophagogastroduodenoscopy and colonoscopy biopsies revealed Toxoplasma gondii, confirmed by immunostain. Symptoms completely resolved following treatment with pyrimethamine, sulfadiazine, and leucovorin. This case highlights the importance of including toxoplasmosis in the differential diagnosis of any immunocompromised individual presenting with gastrointestinal symptoms. |
format | Article |
id | doaj-art-6527c56efd03430c95affd53307a2144 |
institution | Kabale University |
issn | 2090-6528 2090-6536 |
language | English |
publishDate | 2017-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Gastrointestinal Medicine |
spelling | doaj-art-6527c56efd03430c95affd53307a21442025-02-03T07:26:11ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/34910873491087Diarrhea as a Presenting Symptom of Disseminated ToxoplasmosisMatthew Glover0Zhouwen Tang1Robert Sealock2Shilpa Jain3Baylor College of Medicine, Houston, TX, USABaylor College of Medicine, Houston, TX, USABaylor College of Medicine, Houston, TX, USABaylor College of Medicine, Houston, TX, USADisseminated toxoplasmosis is uncommon in both immunocompetent and immunocompromised hosts with gastrointestinal involvement being rarely described. We report a case of disseminated gastrointestinal toxoplasmosis in an immunocompromised man who presented with one month of diarrhea and abdominal pain. Imaging showed thickening of the ascending colon and cecum. Esophagogastroduodenoscopy and colonoscopy biopsies revealed Toxoplasma gondii, confirmed by immunostain. Symptoms completely resolved following treatment with pyrimethamine, sulfadiazine, and leucovorin. This case highlights the importance of including toxoplasmosis in the differential diagnosis of any immunocompromised individual presenting with gastrointestinal symptoms.http://dx.doi.org/10.1155/2017/3491087 |
spellingShingle | Matthew Glover Zhouwen Tang Robert Sealock Shilpa Jain Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis Case Reports in Gastrointestinal Medicine |
title | Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis |
title_full | Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis |
title_fullStr | Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis |
title_full_unstemmed | Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis |
title_short | Diarrhea as a Presenting Symptom of Disseminated Toxoplasmosis |
title_sort | diarrhea as a presenting symptom of disseminated toxoplasmosis |
url | http://dx.doi.org/10.1155/2017/3491087 |
work_keys_str_mv | AT matthewglover diarrheaasapresentingsymptomofdisseminatedtoxoplasmosis AT zhouwentang diarrheaasapresentingsymptomofdisseminatedtoxoplasmosis AT robertsealock diarrheaasapresentingsymptomofdisseminatedtoxoplasmosis AT shilpajain diarrheaasapresentingsymptomofdisseminatedtoxoplasmosis |