Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq
Background Despite saving millions of lives through blood transfusion, transfusion-transmissible infections (TTIs) still threaten the lives of patients requiring blood transfusion. Hence, screening blood donors and studying the prevalence of TTIs among blood donors may display the burden of these di...
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BMJ Publishing Group
2023-07-01
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| Series: | BMJ Open Gastroenterology |
| Online Access: | https://bmjopengastro.bmj.com/content/10/1/e000968.full |
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| author | Khairallah A S Mohammed Maha M Hameed Abdullah H Mousa Amar T Saleh |
| author_facet | Khairallah A S Mohammed Maha M Hameed Abdullah H Mousa Amar T Saleh |
| author_sort | Khairallah A S Mohammed |
| collection | DOAJ |
| description | Background Despite saving millions of lives through blood transfusion, transfusion-transmissible infections (TTIs) still threaten the lives of patients requiring blood transfusion. Hence, screening blood donors and studying the prevalence of TTIs among blood donors may display the burden of these diseases among our population. The aim of this study was to assess the seroprevalence rates of transfusion transmitted infections among blood donors in Basra, Iraq from 2019 to 2021 as groundwork for providing safe blood transfusion in Iraq.Methods A cross-sectional study was carried out in the blood banks in Basra, Iraq from 1 January 2019 to 31 December 2021. A total of 197 898 samples were collected and screened for hepatitis B surface antigen (HBsAg), anti-hepatitis B core (HBc), anti-hepatitis C virus (HCV) and syphilis immunologically.Results The prevalence rates of seropositive of viral hepatitis for the year 2019, 2020, 2021 were as following: hepatitis B virus (HBV) rates 1.54%, 1.45% and 1.14% with significant declined trend by 26%; anti-HCV rates were 0.14, 0.12 and 0.11% with significant declined trend by 21.4%; and the syphilis rates were 0.38, 0.47, 0.36 with marked declined trend 5.3%, respectively.Of those donors showed HBV positive, 2503 (1.26%) had positive anti-HBc results, while only 173 (0.0874) showed positive test results for both anti-HBc and HBsAg.Conclusion Prevalence rates of viral hepatitis and syphilis showed a steady decline between 2019 and 2021, and these rates were much lower in Basra than in other parts of Iraq and neighbouring countries. The importance of using the anti-HBc test in the screening of blood donors was indicated in this study. These findings would contribute in improving the understanding of TTIs epidemiology and supporting health authorities controlling bloodborne diseases. |
| format | Article |
| id | doaj-art-65146879eb324c559e35ae9f01af1dd3 |
| institution | Kabale University |
| issn | 2054-4774 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Gastroenterology |
| spelling | doaj-art-65146879eb324c559e35ae9f01af1dd32025-02-01T19:55:09ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742023-07-0110110.1136/bmjgast-2022-000968Prevalence and trends of transfusion transmissible infections among blood donors in Basra, IraqKhairallah A S Mohammed0Maha M Hameed1Abdullah H Mousa2Amar T Saleh3Department of Medical Lab Technology, Southern Technical University, Basra, IraqSouthern Technical University, Basra, IraqSouthern Technical University, Basra, IraqSouthern Technical University, Basra, IraqBackground Despite saving millions of lives through blood transfusion, transfusion-transmissible infections (TTIs) still threaten the lives of patients requiring blood transfusion. Hence, screening blood donors and studying the prevalence of TTIs among blood donors may display the burden of these diseases among our population. The aim of this study was to assess the seroprevalence rates of transfusion transmitted infections among blood donors in Basra, Iraq from 2019 to 2021 as groundwork for providing safe blood transfusion in Iraq.Methods A cross-sectional study was carried out in the blood banks in Basra, Iraq from 1 January 2019 to 31 December 2021. A total of 197 898 samples were collected and screened for hepatitis B surface antigen (HBsAg), anti-hepatitis B core (HBc), anti-hepatitis C virus (HCV) and syphilis immunologically.Results The prevalence rates of seropositive of viral hepatitis for the year 2019, 2020, 2021 were as following: hepatitis B virus (HBV) rates 1.54%, 1.45% and 1.14% with significant declined trend by 26%; anti-HCV rates were 0.14, 0.12 and 0.11% with significant declined trend by 21.4%; and the syphilis rates were 0.38, 0.47, 0.36 with marked declined trend 5.3%, respectively.Of those donors showed HBV positive, 2503 (1.26%) had positive anti-HBc results, while only 173 (0.0874) showed positive test results for both anti-HBc and HBsAg.Conclusion Prevalence rates of viral hepatitis and syphilis showed a steady decline between 2019 and 2021, and these rates were much lower in Basra than in other parts of Iraq and neighbouring countries. The importance of using the anti-HBc test in the screening of blood donors was indicated in this study. These findings would contribute in improving the understanding of TTIs epidemiology and supporting health authorities controlling bloodborne diseases.https://bmjopengastro.bmj.com/content/10/1/e000968.full |
| spellingShingle | Khairallah A S Mohammed Maha M Hameed Abdullah H Mousa Amar T Saleh Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq BMJ Open Gastroenterology |
| title | Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq |
| title_full | Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq |
| title_fullStr | Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq |
| title_full_unstemmed | Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq |
| title_short | Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq |
| title_sort | prevalence and trends of transfusion transmissible infections among blood donors in basra iraq |
| url | https://bmjopengastro.bmj.com/content/10/1/e000968.full |
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