Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis

Abstract Multiple sclerosis (MS) unfavorably affects working capacity. The Comprehensive International Classification of Functioning, Disability and Health Core Set for MS (cICF-MS), issued by the World Health Organization, has not yet been extended to evaluate working capacity level (WCL). To evalu...

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Main Authors: Daiva Valadkevičienė, Irena Žukauskaitė, Indre Bileviciute-Ljungar, Rasa Kizlaitienė, Dalius Jatužis, Virginija Danylaitė Karrenbauer
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87827-6
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author Daiva Valadkevičienė
Irena Žukauskaitė
Indre Bileviciute-Ljungar
Rasa Kizlaitienė
Dalius Jatužis
Virginija Danylaitė Karrenbauer
author_facet Daiva Valadkevičienė
Irena Žukauskaitė
Indre Bileviciute-Ljungar
Rasa Kizlaitienė
Dalius Jatužis
Virginija Danylaitė Karrenbauer
author_sort Daiva Valadkevičienė
collection DOAJ
description Abstract Multiple sclerosis (MS) unfavorably affects working capacity. The Comprehensive International Classification of Functioning, Disability and Health Core Set for MS (cICF-MS), issued by the World Health Organization, has not yet been extended to evaluate working capacity level (WCL). To evaluate the relative importance of cICF-MS categories in relation to WCL. Persons with MS (PwMS), N = 129, who had been referred to Lithuania’s Disability and Working Capacity Assessment Office for WCL determination, were divided into three groups according to the percentage of remaining WCL (WCL1 had 0–25%, WCL2 had 30–40%, and WCL3 had 45–55%). Data regarding the cICF-MS categories were collected through telephone interviews and patient documentation. Using the fractional ranking method, the mean values of cICF-MS impairment were ranked from the most severely affected to the least affected (rank 1–93). Ranks with the 10 highest mean values of impairment severity in each WCL group were included in a descriptive analysis. In the WCL1 and WCL2 groups, the most-affected cICF-MS categories reflected disability related to gait and motor function. The WCL3 group presented with pain, fatigue, and impairments to visual acuity, psychic stability, urination, and memory. This study has identified specific cICF-MS impairment profiles based on remaining WCL.
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spelling doaj-art-64fbebc599da4c9aada2199f7c56d94a2025-02-02T12:21:15ZengNature PortfolioScientific Reports2045-23222025-01-0115111110.1038/s41598-025-87827-6Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosisDaiva Valadkevičienė0Irena Žukauskaitė1Indre Bileviciute-Ljungar2Rasa Kizlaitienė3Dalius Jatužis4Virginija Danylaitė Karrenbauer5Clinic of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius UniversityInstitute of Psychology, Faculty of Philosophy, Vilnius UniversityDepartment of Clinical Science, Karolinska InstitutetClinic of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius UniversityClinic of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius UniversityDepartment of Clinical Neuroscience, Karolinska InstitutetAbstract Multiple sclerosis (MS) unfavorably affects working capacity. The Comprehensive International Classification of Functioning, Disability and Health Core Set for MS (cICF-MS), issued by the World Health Organization, has not yet been extended to evaluate working capacity level (WCL). To evaluate the relative importance of cICF-MS categories in relation to WCL. Persons with MS (PwMS), N = 129, who had been referred to Lithuania’s Disability and Working Capacity Assessment Office for WCL determination, were divided into three groups according to the percentage of remaining WCL (WCL1 had 0–25%, WCL2 had 30–40%, and WCL3 had 45–55%). Data regarding the cICF-MS categories were collected through telephone interviews and patient documentation. Using the fractional ranking method, the mean values of cICF-MS impairment were ranked from the most severely affected to the least affected (rank 1–93). Ranks with the 10 highest mean values of impairment severity in each WCL group were included in a descriptive analysis. In the WCL1 and WCL2 groups, the most-affected cICF-MS categories reflected disability related to gait and motor function. The WCL3 group presented with pain, fatigue, and impairments to visual acuity, psychic stability, urination, and memory. This study has identified specific cICF-MS impairment profiles based on remaining WCL.https://doi.org/10.1038/s41598-025-87827-6Multiple sclerosis (MS)International classification of functioning, disability and health (ICF)Comprehensive ICF core set for multiple sclerosisWorking capacity levelDisability
spellingShingle Daiva Valadkevičienė
Irena Žukauskaitė
Indre Bileviciute-Ljungar
Rasa Kizlaitienė
Dalius Jatužis
Virginija Danylaitė Karrenbauer
Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis
Scientific Reports
Multiple sclerosis (MS)
International classification of functioning, disability and health (ICF)
Comprehensive ICF core set for multiple sclerosis
Working capacity level
Disability
title Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis
title_full Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis
title_fullStr Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis
title_full_unstemmed Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis
title_short Working capacity level defines the specific impairment profile of the comprehensive ICF core set for multiple sclerosis
title_sort working capacity level defines the specific impairment profile of the comprehensive icf core set for multiple sclerosis
topic Multiple sclerosis (MS)
International classification of functioning, disability and health (ICF)
Comprehensive ICF core set for multiple sclerosis
Working capacity level
Disability
url https://doi.org/10.1038/s41598-025-87827-6
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