Improving doublet cell removal efficiency through multiple algorithm runs
Doublets are a key confounding factor in the analysis of scRNA-seq data, as they can interfere with differential expression analysis and disrupt developmental trajectories. However, due to the randomness of the algorithms, most doublet removal methods still leave a certain proportion of doublets aft...
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Main Authors: | Yong She, Chaoye Wang, Qi Zhao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S200103702500011X |
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