Accumulation of alpha-synuclein pathology in the liver exhibits post-translational modifications associated with Parkinson’s disease
Summary: Accumulating evidence demonstrates that alpha-synuclein (α-syn) pathology associated with Parkinson’s disease (PD) is not limited to the brain, as it also appears in a select number of peripheral tissues including the liver. In this study, we identified a number of PD-associated α-syn post-...
Saved in:
| Main Authors: | Martin Hallbeck, Sara Ekmark-Lewén, Philipp J. Kahle, Martin Ingelsson, Juan F. Reyes |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
|
| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224026750 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Protocol for the intracerebral injection of AAV-α-synuclein plus poly(ADP-ribose) to generate a Parkinson’s disease monkey model
by: Shuyi Liu, et al.
Published: (2025-03-01) -
TNF-α-NF-κB activation through pathological α-Synuclein disrupts the BBB and exacerbates axonopathy
by: Min-Tae Jeon, et al.
Published: (2025-07-01) -
Frontal gamma-alpha ratio reveals neural oscillatory mechanism of attention shifting in tinnitus
by: Xueji Feng, et al.
Published: (2025-03-01) -
Alpha-synuclein abundance and localization are regulated by the RNA-binding protein PUMILIO1
by: Maximilian Cabaj, et al.
Published: (2025-08-01) -
Early synaptic dysfunction of striatal parvalbumin interneurons in a mouse model of Parkinson’s disease
by: Quansheng He, et al.
Published: (2024-11-01)