Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate
Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion that may arise from the oral mucosa consisting in an ulcerative lesion usually localized in the tongue or cheek. Palate localization is very rare. <b>Background</b>/<b>Objectives</b>: The aim...
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2025-01-01
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| author | Giacomo Setti Stefania Caramaschi Giuseppe Barile Antonio d’Amati Marta Forte Giuseppe D’Albis Pierantonio Bellini Giovanna Garuti Luisa Limongelli Saverio Capodiferro |
| author_facet | Giacomo Setti Stefania Caramaschi Giuseppe Barile Antonio d’Amati Marta Forte Giuseppe D’Albis Pierantonio Bellini Giovanna Garuti Luisa Limongelli Saverio Capodiferro |
| author_sort | Giacomo Setti |
| collection | DOAJ |
| description | Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion that may arise from the oral mucosa consisting in an ulcerative lesion usually localized in the tongue or cheek. Palate localization is very rare. <b>Background</b>/<b>Objectives</b>: The aim of this study is to describe a case of TUGSE occurring in the hard palate of an 83 y.o. female patient, manifesting as a non-painful growing palatal lesion approximately of 3.5 × 2 cm with firm consistency and a central area of erosion and erythema, the difficulties in clinical diagnosis, and the criteria for the differential diagnosis. Also, considering the rare occurrence of TUGSE in the palate, we performed a review of the literature too. <b>Methods</b>: A comprehensive review of the literature was conducted following the 2020 PRISMA guidelines and a total of seven records were identified as matching the inclusion criteria of this study. <b>Results Conclusions</b>: Although TUGSE is a benign lesion, the clinical presentation as a proliferative and ulcerative lesion may be challenging for clinicians mainly when arising in rare sites of occurrence (e.g., the hard palate). |
| format | Article |
| id | doaj-art-64bcba640d734a5184cf676e1e0af1c1 |
| institution | Kabale University |
| issn | 2075-4418 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-64bcba640d734a5184cf676e1e0af1c12025-01-24T13:29:05ZengMDPI AGDiagnostics2075-44182025-01-0115219910.3390/diagnostics15020199Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard PalateGiacomo Setti0Stefania Caramaschi1Giuseppe Barile2Antonio d’Amati3Marta Forte4Giuseppe D’Albis5Pierantonio Bellini6Giovanna Garuti7Luisa Limongelli8Saverio Capodiferro9Dentistry and Oral-Maxillofacial Surgery, Department of Surgical, Medical, Dental, and Morphological Science, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, ItalyDepartment of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, ItalyDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, ItalyDentistry and Oral-Maxillofacial Surgery, Department of Surgical, Medical, Dental, and Morphological Science, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, ItalyDentistry and Oral-Maxillofacial Surgery, Department of Surgical, Medical, Dental, and Morphological Science, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, ItalyTraumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion that may arise from the oral mucosa consisting in an ulcerative lesion usually localized in the tongue or cheek. Palate localization is very rare. <b>Background</b>/<b>Objectives</b>: The aim of this study is to describe a case of TUGSE occurring in the hard palate of an 83 y.o. female patient, manifesting as a non-painful growing palatal lesion approximately of 3.5 × 2 cm with firm consistency and a central area of erosion and erythema, the difficulties in clinical diagnosis, and the criteria for the differential diagnosis. Also, considering the rare occurrence of TUGSE in the palate, we performed a review of the literature too. <b>Methods</b>: A comprehensive review of the literature was conducted following the 2020 PRISMA guidelines and a total of seven records were identified as matching the inclusion criteria of this study. <b>Results Conclusions</b>: Although TUGSE is a benign lesion, the clinical presentation as a proliferative and ulcerative lesion may be challenging for clinicians mainly when arising in rare sites of occurrence (e.g., the hard palate).https://www.mdpi.com/2075-4418/15/2/199TUGSEoral cavityoral pathology |
| spellingShingle | Giacomo Setti Stefania Caramaschi Giuseppe Barile Antonio d’Amati Marta Forte Giuseppe D’Albis Pierantonio Bellini Giovanna Garuti Luisa Limongelli Saverio Capodiferro Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate Diagnostics TUGSE oral cavity oral pathology |
| title | Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate |
| title_full | Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate |
| title_fullStr | Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate |
| title_full_unstemmed | Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate |
| title_short | Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate |
| title_sort | diagnostic challenges of traumatic ulcerative granuloma with stromal eosinophilia in the hard palate |
| topic | TUGSE oral cavity oral pathology |
| url | https://www.mdpi.com/2075-4418/15/2/199 |
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