The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
Historically, neoadjuvant chemotherapy has been used to treat patients with advanced breast disease in an attempt to convert them into candidates for breast conservation surgery. The ultimate goal of histopathologic examination of the specimens removed after neoadjuvant chemotherapy is the identific...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | International Journal of Breast Cancer |
Online Access: | http://dx.doi.org/10.1155/2012/361707 |
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author | Julio A. Ibarra |
author_facet | Julio A. Ibarra |
author_sort | Julio A. Ibarra |
collection | DOAJ |
description | Historically, neoadjuvant chemotherapy has been used to treat patients with advanced breast disease in an attempt to convert them into candidates for breast conservation surgery. The ultimate goal of histopathologic examination of the specimens removed after neoadjuvant chemotherapy is the identification of either residual disease or positive identification of the tumor bed. We report a series of 40 patients treated with neoadjuvant chemotherapy and evaluation of the surgical specimens by a combination of standard histopathology and the use of large format histopathology techniques. |
format | Article |
id | doaj-art-64a20247d905419f918c2b62c8269437 |
institution | Kabale University |
issn | 2090-3170 2090-3189 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Breast Cancer |
spelling | doaj-art-64a20247d905419f918c2b62c82694372025-02-03T01:10:39ZengWileyInternational Journal of Breast Cancer2090-31702090-31892012-01-01201210.1155/2012/361707361707The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 CasesJulio A. Ibarra0Department of Pathology, University of California and Irvine and MemorialCare Breast Center, Orange Coast Memorial Medical Center, 9920 Talbert Avenue, Fountain Valley, CA 92708, USAHistorically, neoadjuvant chemotherapy has been used to treat patients with advanced breast disease in an attempt to convert them into candidates for breast conservation surgery. The ultimate goal of histopathologic examination of the specimens removed after neoadjuvant chemotherapy is the identification of either residual disease or positive identification of the tumor bed. We report a series of 40 patients treated with neoadjuvant chemotherapy and evaluation of the surgical specimens by a combination of standard histopathology and the use of large format histopathology techniques.http://dx.doi.org/10.1155/2012/361707 |
spellingShingle | Julio A. Ibarra The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases International Journal of Breast Cancer |
title | The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases |
title_full | The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases |
title_fullStr | The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases |
title_full_unstemmed | The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases |
title_short | The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases |
title_sort | value of combined large format histopathology technique to assess the surgically removed breast tissue following neoadjuvant chemotherapy a single institution study of 40 cases |
url | http://dx.doi.org/10.1155/2012/361707 |
work_keys_str_mv | AT julioaibarra thevalueofcombinedlargeformathistopathologytechniquetoassessthesurgicallyremovedbreasttissuefollowingneoadjuvantchemotherapyasingleinstitutionstudyof40cases AT julioaibarra valueofcombinedlargeformathistopathologytechniquetoassessthesurgicallyremovedbreasttissuefollowingneoadjuvantchemotherapyasingleinstitutionstudyof40cases |