The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases

Historically, neoadjuvant chemotherapy has been used to treat patients with advanced breast disease in an attempt to convert them into candidates for breast conservation surgery. The ultimate goal of histopathologic examination of the specimens removed after neoadjuvant chemotherapy is the identific...

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Main Author: Julio A. Ibarra
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2012/361707
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author Julio A. Ibarra
author_facet Julio A. Ibarra
author_sort Julio A. Ibarra
collection DOAJ
description Historically, neoadjuvant chemotherapy has been used to treat patients with advanced breast disease in an attempt to convert them into candidates for breast conservation surgery. The ultimate goal of histopathologic examination of the specimens removed after neoadjuvant chemotherapy is the identification of either residual disease or positive identification of the tumor bed. We report a series of 40 patients treated with neoadjuvant chemotherapy and evaluation of the surgical specimens by a combination of standard histopathology and the use of large format histopathology techniques.
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publishDate 2012-01-01
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series International Journal of Breast Cancer
spelling doaj-art-64a20247d905419f918c2b62c82694372025-02-03T01:10:39ZengWileyInternational Journal of Breast Cancer2090-31702090-31892012-01-01201210.1155/2012/361707361707The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 CasesJulio A. Ibarra0Department of Pathology, University of California and Irvine and MemorialCare Breast Center, Orange Coast Memorial Medical Center, 9920 Talbert Avenue, Fountain Valley, CA 92708, USAHistorically, neoadjuvant chemotherapy has been used to treat patients with advanced breast disease in an attempt to convert them into candidates for breast conservation surgery. The ultimate goal of histopathologic examination of the specimens removed after neoadjuvant chemotherapy is the identification of either residual disease or positive identification of the tumor bed. We report a series of 40 patients treated with neoadjuvant chemotherapy and evaluation of the surgical specimens by a combination of standard histopathology and the use of large format histopathology techniques.http://dx.doi.org/10.1155/2012/361707
spellingShingle Julio A. Ibarra
The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
International Journal of Breast Cancer
title The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
title_full The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
title_fullStr The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
title_full_unstemmed The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
title_short The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases
title_sort value of combined large format histopathology technique to assess the surgically removed breast tissue following neoadjuvant chemotherapy a single institution study of 40 cases
url http://dx.doi.org/10.1155/2012/361707
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