Systemic inflammatory response index mediates the association between stroke and hypertension: a cross-sectional study from NHANES 2001 to 2016

Systemic inflammatory response index mediates the association between stroke and hypertension: a cross-sectional study from NHANES 2001 to 2016

BackgroundSystemic inflammation plays a vital role in the development of hypertension and stroke. The systemic immune response index (SIRI), calculated from the numbers of neutrophils, monocytes, and lymphocytes, is a promising indicator of immune dysregulation. Yet, its role in mediating the link b...

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Bibliographic Details
Main Authors: Mingzhu Tang, Fangming Diao, Yaxian Dong, Jianpeng Lin, Tiezhu Wang, Lihua Yang, Xuanming Lai, Xiaolian Chen, Jinxi Zuo, Junyang Xu, Hongting Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neurology
Subjects:
stroke
hypertension
systemic immune response index
inflammation
cross-sectional study
mediation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1603241/full
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