Prognostic value of hypoxia-inducible factor-1 alpha gene polymorphism in patients with heart failure with preserved ejection fraction and obstructive sleep apnea

Prognostic value of hypoxia-inducible factor-1 alpha gene polymorphism in patients with heart failure with preserved ejection fraction and obstructive sleep apnea

Aim. To study the associations of hypoxia-inducible factor-1 alpha (HIF-1α) gene polymorphism (rs11549465) with the clinical course of heart failure (HF) with reserved ejection fraction (HFpEF) in patients with obesity and moderate and severe obstructive sleep apnea (OSA).Material and methods. The s...

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Main Authors: A. V. Yakovlev, R. S. Chernyshev, K. S. Sakhonchik, S. N. Shilov, E. V. Grakova, K. V. Kop’eva, A. T. Teplyakov, I. A. Efremov, M. S. Kessler, N. F. Yakovleva, I. A. Grebenkina
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2022-08-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
polymorphism
<i>hif1a</i>
hif-1α
heart failure
obstructive sleep apnea
genotype
prognosis
Online Access:https://cardiovascular.elpub.ru/jour/article/view/3276
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