Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns
The objective: to characterize tuberculosis in children exposed todrug-resistant tuberculosis in St. Petersburg.Subjects and methods. 51 children exposed to tuberculosis in their families were enrolled into the study; of them, 23 children were exposed to MDR TB; 7 children were exposed to other drug...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2019-10-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1332 |
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| author | M. E. Lozovskaya A. S. Kurova E. B. Vasilieva L. V. Klochkova N. A. Nikiforenko A. V. Mosina |
| author_facet | M. E. Lozovskaya A. S. Kurova E. B. Vasilieva L. V. Klochkova N. A. Nikiforenko A. V. Mosina |
| author_sort | M. E. Lozovskaya |
| collection | DOAJ |
| description | The objective: to characterize tuberculosis in children exposed todrug-resistant tuberculosis in St. Petersburg.Subjects and methods. 51 children exposed to tuberculosis in their families were enrolled into the study; of them, 23 children were exposed to MDR TB; 7 children were exposed to other drug resistant patterns of the disease; 21 children were exposed to drug susceptible tuberculosis.Results. In St. Petersburg in 2015-2017, MDR TB cases prevailed among adult index cases to whom children were exposed. The course of tuberculosis was the most severe in children exposed to MDR TB. Such children were treated with regimen IV with high efficacy achieved, taking into account the severity of the disease, age, concurrent disorders, and tolerability of the drugs, as well as drug resistance of the index case. |
| format | Article |
| id | doaj-art-64853c4f51d2484a8d1f5af00d04b699 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2019-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-64853c4f51d2484a8d1f5af00d04b6992025-08-20T02:16:01ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-10-01979222710.21292/2075-1230-2019-97-9-22-271332Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patternsM. E. Lozovskaya0A. S. Kurova1E. B. Vasilieva2L. V. Klochkova3N. A. Nikiforenko4A. V. Mosina5St. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversityChildren Infectious Hospital no. 3The objective: to characterize tuberculosis in children exposed todrug-resistant tuberculosis in St. Petersburg.Subjects and methods. 51 children exposed to tuberculosis in their families were enrolled into the study; of them, 23 children were exposed to MDR TB; 7 children were exposed to other drug resistant patterns of the disease; 21 children were exposed to drug susceptible tuberculosis.Results. In St. Petersburg in 2015-2017, MDR TB cases prevailed among adult index cases to whom children were exposed. The course of tuberculosis was the most severe in children exposed to MDR TB. Such children were treated with regimen IV with high efficacy achieved, taking into account the severity of the disease, age, concurrent disorders, and tolerability of the drugs, as well as drug resistance of the index case.https://www.tibl-journal.com/jour/article/view/1332tuberculosis in childrennidus of tuberculosisdrug resistancetuberculosis chemotherapy |
| spellingShingle | M. E. Lozovskaya A. S. Kurova E. B. Vasilieva L. V. Klochkova N. A. Nikiforenko A. V. Mosina Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns Туберкулез и болезни лёгких tuberculosis in children nidus of tuberculosis drug resistance tuberculosis chemotherapy |
| title | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_full | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_fullStr | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_full_unstemmed | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_short | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_sort | specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| topic | tuberculosis in children nidus of tuberculosis drug resistance tuberculosis chemotherapy |
| url | https://www.tibl-journal.com/jour/article/view/1332 |
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