Prediction of Deleterious Nonsynonymous Single-Nucleotide Polymorphism for Human Diseases
The identification of genetic variants that are responsible for human inherited diseases is a fundamental problem in human and medical genetics. As a typical type of genetic variation, nonsynonymous single-nucleotide polymorphisms (nsSNPs) occurring in protein coding regions may alter the encoded am...
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Main Authors: | Jiaxin Wu, Rui Jiang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1155/2013/675851 |
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