Coronavirus Disease-19 associated arthritis – An observational study
Background: The coronavirus disease or COVID-19 pandemic is the major global health crisis of the present time. Various rheumatological manifestations have been reported during or after COVID-19 infection, but data are scarce. In this observational study, we have tried to analyze the clinical charac...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=2;spage=153;epage=156;aulast= |
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| author | Debanjali Sinha Sumantro Mondal Alakendu Ghosh |
| author_facet | Debanjali Sinha Sumantro Mondal Alakendu Ghosh |
| author_sort | Debanjali Sinha |
| collection | DOAJ |
| description | Background: The coronavirus disease or COVID-19 pandemic is the major global health crisis of the present time. Various rheumatological manifestations have been reported during or after COVID-19 infection, but data are scarce. In this observational study, we have tried to analyze the clinical characteristics of COVID-19 associated arthralgia/arthritis.
Methods: We have collected the clinical data of 14 patients over the past 6 months who have developed arthralgia or arthritis during or after symptomatic COVID-19 infection, proven by a positive reverse transcription-polymerase chain reaction test from nasopharyngeal swab.
Results: The most common symptoms during COVID-19 infection in the 14 patients were fever and myalgia, being present in 92.8% and 64.3% patients, respectively. Arthralgia/arthritis occurred at a mean interval of 20 days (range: 0–60 days). Knee was the most commonly involved joint (78.6%), followed by the wrist and metacarpophalangeal joints (each in 57.1%). Enthesitis was documented in 21.4% patients. The mean duration of COVID-19 associated arthralgia or arthritis was 53.9 days (range: 7–210 days). In 85.7% patients, joint pains improved within 2 months; in only a small proportion of patients (14.3%), joint pains persisted after 6 months. Nonsteroidal anti-inflammatory drugs (NSAIDs) (given in 64.3% patients) and corticosteroids (in 50%) were the most commonly prescribed and effective treatment options.
Conclusion: COVID-19 infections mostly caused reactive arthritis, though acute and chronic arthritis is also seen. In the majority of cases, arthritis started about 3 weeks after COVID-19 infection and subsided within 2 months. NSAIDs and corticosteroids are the most effective treatment options. |
| format | Article |
| id | doaj-art-641bbf3cb756405399f6bd4dfbafe7e2 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-641bbf3cb756405399f6bd4dfbafe7e22025-02-03T10:55:04ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012022-01-0117215315610.4103/injr.injr_133_21Coronavirus Disease-19 associated arthritis – An observational studyDebanjali SinhaSumantro MondalAlakendu GhoshBackground: The coronavirus disease or COVID-19 pandemic is the major global health crisis of the present time. Various rheumatological manifestations have been reported during or after COVID-19 infection, but data are scarce. In this observational study, we have tried to analyze the clinical characteristics of COVID-19 associated arthralgia/arthritis. Methods: We have collected the clinical data of 14 patients over the past 6 months who have developed arthralgia or arthritis during or after symptomatic COVID-19 infection, proven by a positive reverse transcription-polymerase chain reaction test from nasopharyngeal swab. Results: The most common symptoms during COVID-19 infection in the 14 patients were fever and myalgia, being present in 92.8% and 64.3% patients, respectively. Arthralgia/arthritis occurred at a mean interval of 20 days (range: 0–60 days). Knee was the most commonly involved joint (78.6%), followed by the wrist and metacarpophalangeal joints (each in 57.1%). Enthesitis was documented in 21.4% patients. The mean duration of COVID-19 associated arthralgia or arthritis was 53.9 days (range: 7–210 days). In 85.7% patients, joint pains improved within 2 months; in only a small proportion of patients (14.3%), joint pains persisted after 6 months. Nonsteroidal anti-inflammatory drugs (NSAIDs) (given in 64.3% patients) and corticosteroids (in 50%) were the most commonly prescribed and effective treatment options. Conclusion: COVID-19 infections mostly caused reactive arthritis, though acute and chronic arthritis is also seen. In the majority of cases, arthritis started about 3 weeks after COVID-19 infection and subsided within 2 months. NSAIDs and corticosteroids are the most effective treatment options.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=2;spage=153;epage=156;aulast=arthralgiaarthritiscoronavirus disease-19reactive arthritis |
| spellingShingle | Debanjali Sinha Sumantro Mondal Alakendu Ghosh Coronavirus Disease-19 associated arthritis – An observational study Indian Journal of Rheumatology arthralgia arthritis coronavirus disease-19 reactive arthritis |
| title | Coronavirus Disease-19 associated arthritis – An observational study |
| title_full | Coronavirus Disease-19 associated arthritis – An observational study |
| title_fullStr | Coronavirus Disease-19 associated arthritis – An observational study |
| title_full_unstemmed | Coronavirus Disease-19 associated arthritis – An observational study |
| title_short | Coronavirus Disease-19 associated arthritis – An observational study |
| title_sort | coronavirus disease 19 associated arthritis an observational study |
| topic | arthralgia arthritis coronavirus disease-19 reactive arthritis |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=2;spage=153;epage=156;aulast= |
| work_keys_str_mv | AT debanjalisinha coronavirusdisease19associatedarthritisanobservationalstudy AT sumantromondal coronavirusdisease19associatedarthritisanobservationalstudy AT alakendughosh coronavirusdisease19associatedarthritisanobservationalstudy |