A Conserved Di-Lysine Motif in the E2 Transactivation Domain Regulates MmuPV1 Replication and Disease Progression

A Conserved Di-Lysine Motif in the E2 Transactivation Domain Regulates MmuPV1 Replication and Disease Progression

The papillomavirus E2 protein regulates the transcription, replication, and segregation of viral episomes within the host cell. A multitude of post-translational modifications have been identified which control E2 functions. A highly conserved di-lysine motif within the transactivation domain (TAD)...

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Bibliographic Details
Main Authors: Jessica Gonzalez, Marsha DeSmet, Elliot J. Androphy
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pathogens
Subjects:
papillomavirus
HPV
MmuPV1
E2
post-translational modification
Online Access:https://www.mdpi.com/2076-0817/14/1/84
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