Cytomegalovirus Retinitis in Primary Immune Deficiency Disease
Introduction. To report an unusual case of CMV retinitis in Primary Immune Deficiency Disease (PIDD). Case Report. 13-year-old child with combined T and B cell deficiencies was diagnosed of bilateral zone 1 CMV retinitis. Intravitreal injections were unable to be given in a regular and timely manner...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/8125806 |
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| _version_ | 1832562812986064896 |
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| author | Jia Jeane Ngai Ka Lung Chong Shelina Oli Mohamed |
| author_facet | Jia Jeane Ngai Ka Lung Chong Shelina Oli Mohamed |
| author_sort | Jia Jeane Ngai |
| collection | DOAJ |
| description | Introduction. To report an unusual case of CMV retinitis in Primary Immune Deficiency Disease (PIDD). Case Report. 13-year-old child with combined T and B cell deficiencies was diagnosed of bilateral zone 1 CMV retinitis. Intravitreal injections were unable to be given in a regular and timely manner under general anaesthesia due to her underlying systemic disease. The child was treated with intravenous ganciclovir for 8 weeks until eventual resolution of the retinitis. However, visual acuity deteriorated due to progressive optic nerve involvement. Conclusion. Paediatric patients often do not notice subtle symptoms of CMV retinitis. Although ocular manifestations are uncommon in PIDD, recognition and high index of suspicion will allow for timely referral, diagnosis, and treatment to be instituted for better visual outcomes. |
| format | Article |
| id | doaj-art-63fc625ccc704e7f9a6f92f18864a510 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-63fc625ccc704e7f9a6f92f18864a5102025-02-03T01:21:41ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302018-01-01201810.1155/2018/81258068125806Cytomegalovirus Retinitis in Primary Immune Deficiency DiseaseJia Jeane Ngai0Ka Lung Chong1Shelina Oli Mohamed2Department of Ophthalmology, Hospital Bintulu, Sarawak, MalaysiaDepartment of Ophthalmology, Hospital Bintulu, Sarawak, MalaysiaDepartment of Ophthalmology, Hospital Shah Alam, Selangor, MalaysiaIntroduction. To report an unusual case of CMV retinitis in Primary Immune Deficiency Disease (PIDD). Case Report. 13-year-old child with combined T and B cell deficiencies was diagnosed of bilateral zone 1 CMV retinitis. Intravitreal injections were unable to be given in a regular and timely manner under general anaesthesia due to her underlying systemic disease. The child was treated with intravenous ganciclovir for 8 weeks until eventual resolution of the retinitis. However, visual acuity deteriorated due to progressive optic nerve involvement. Conclusion. Paediatric patients often do not notice subtle symptoms of CMV retinitis. Although ocular manifestations are uncommon in PIDD, recognition and high index of suspicion will allow for timely referral, diagnosis, and treatment to be instituted for better visual outcomes.http://dx.doi.org/10.1155/2018/8125806 |
| spellingShingle | Jia Jeane Ngai Ka Lung Chong Shelina Oli Mohamed Cytomegalovirus Retinitis in Primary Immune Deficiency Disease Case Reports in Ophthalmological Medicine |
| title | Cytomegalovirus Retinitis in Primary Immune Deficiency Disease |
| title_full | Cytomegalovirus Retinitis in Primary Immune Deficiency Disease |
| title_fullStr | Cytomegalovirus Retinitis in Primary Immune Deficiency Disease |
| title_full_unstemmed | Cytomegalovirus Retinitis in Primary Immune Deficiency Disease |
| title_short | Cytomegalovirus Retinitis in Primary Immune Deficiency Disease |
| title_sort | cytomegalovirus retinitis in primary immune deficiency disease |
| url | http://dx.doi.org/10.1155/2018/8125806 |
| work_keys_str_mv | AT jiajeanengai cytomegalovirusretinitisinprimaryimmunedeficiencydisease AT kalungchong cytomegalovirusretinitisinprimaryimmunedeficiencydisease AT shelinaolimohamed cytomegalovirusretinitisinprimaryimmunedeficiencydisease |