Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization
Pulp vitality is extremely important for the tooth viability, since it provides nutrition and acts as biosensor to detect pathogenic stimuli. In the dental clinic, most dental pulp infections are irreversible due to its anatomical position and organization. It is difficult for the body to eliminate...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2010/856087 |
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| _version_ | 1832565511246839808 |
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| author | Weibo Zhang Pamela C. Yelick |
| author_facet | Weibo Zhang Pamela C. Yelick |
| author_sort | Weibo Zhang |
| collection | DOAJ |
| description | Pulp vitality is extremely important for the tooth viability, since it provides nutrition and acts as biosensor to detect pathogenic stimuli. In the dental clinic, most dental pulp infections are irreversible due to its anatomical position and organization. It is difficult for the body to eliminate the infection, which subsequently persists and worsens. The widely used strategy currently in the clinic is to partly or fully remove the contaminated pulp tissue, and fill and seal the void space with synthetic material. Over time, the pulpless tooth, now lacking proper blood supply and nervous system, becomes more vulnerable to injury. Recently, potential for successful pulp regeneration and revascularization therapies is increasing due to accumulated knowledge of stem cells, especially dental pulp stem cells. This paper will review current progress and feasible strategies for dental pulp regeneration and revascularization. |
| format | Article |
| id | doaj-art-63e835129a0c457fab024855d02331ce |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-63e835129a0c457fab024855d02331ce2025-02-03T01:07:25ZengWileyInternational Journal of Dentistry1687-87281687-87362010-01-01201010.1155/2010/856087856087Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and RevascularizationWeibo Zhang0Pamela C. Yelick1Division of Craniofacial and Molecular Genetics, Department of Oral and Maxillofacial Pathology, Tufts University, 136 Harrison Avenue, Room M824, Boston, MA 02111, USADivision of Craniofacial and Molecular Genetics, Department of Oral and Maxillofacial Pathology, Tufts University, 136 Harrison Avenue, Room M824, Boston, MA 02111, USAPulp vitality is extremely important for the tooth viability, since it provides nutrition and acts as biosensor to detect pathogenic stimuli. In the dental clinic, most dental pulp infections are irreversible due to its anatomical position and organization. It is difficult for the body to eliminate the infection, which subsequently persists and worsens. The widely used strategy currently in the clinic is to partly or fully remove the contaminated pulp tissue, and fill and seal the void space with synthetic material. Over time, the pulpless tooth, now lacking proper blood supply and nervous system, becomes more vulnerable to injury. Recently, potential for successful pulp regeneration and revascularization therapies is increasing due to accumulated knowledge of stem cells, especially dental pulp stem cells. This paper will review current progress and feasible strategies for dental pulp regeneration and revascularization.http://dx.doi.org/10.1155/2010/856087 |
| spellingShingle | Weibo Zhang Pamela C. Yelick Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization International Journal of Dentistry |
| title | Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization |
| title_full | Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization |
| title_fullStr | Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization |
| title_full_unstemmed | Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization |
| title_short | Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization |
| title_sort | vital pulp therapy current progress of dental pulp regeneration and revascularization |
| url | http://dx.doi.org/10.1155/2010/856087 |
| work_keys_str_mv | AT weibozhang vitalpulptherapycurrentprogressofdentalpulpregenerationandrevascularization AT pamelacyelick vitalpulptherapycurrentprogressofdentalpulpregenerationandrevascularization |