Current advancements in the mechanisms and animal models of acute exacerbation of pulmonary fibrosis: a systematic review

Current advancements in the mechanisms and animal models of acute exacerbation of pulmonary fibrosis: a systematic review

Characterized by sudden onset, accelerated disease progression, and high mortality rates, acute exacerbation (AE) represents the most critical clinical challenge faced by patients with idiopathic pulmonary fibrosis (IPF). The absence of standardized animal models that recapitulate human disease phen...

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Bibliographic Details
Main Authors: Kai Chen, Hailong Zhang, Zhaoxu Yao, Siyu Tao, Qian Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
animal model
pulmonary fibrosis
acute exacerbation
mechanisms
systematic review
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1501085/full
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