Extracellular Ubiquitin Enhances Autophagy and Inhibits Mitochondrial Apoptosis Pathway to Protect Neurons Against Spinal Cord Ischemic Injury via CXCR4

Extracellular Ubiquitin Enhances Autophagy and Inhibits Mitochondrial Apoptosis Pathway to Protect Neurons Against Spinal Cord Ischemic Injury via CXCR4

Objective Neuronal apoptosis is considered to be a critical process in spinal cord injury (SCI). Despite growing evidence of the antiapoptotic, anti-inflammatory, and modulation of ischemic injury tolerance effects of extracellular ubiquitin (eUb), existing studies have paid less attention to the im...

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Bibliographic Details
Main Authors: Hao Feng, Dehui Chen, Huina Chen, Dingwei Wu, Dandan Wang, Zhengxi Yu, Linquan Zhou, Zhenyu Wang, Wenge Liu
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2025-03-01
Series:Neurospine
Subjects:
spinal cord injury
extracellular ubiquitin
cxcr4
autophagy
mitochondrial apoptosis pathway
Online Access:http://e-neurospine.org/upload/pdf/ns-2448878-439.pdf
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