Impact of Aging in Microglia-Mediated D-Serine Balance in the CNS
A mild chronic inflammatory state, like that observed in aged individuals, affects microglial function, inducing a dysfunctional phenotype that potentiates neuroinflammation and cytotoxicity instead of neuroprotection in response to additional challenges. Given that inflammatory activation of microg...
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Main Authors: | Sebastián Beltrán-Castillo, Jaime Eugenín, Rommy von Bernhardi |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2018/7219732 |
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