Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy
2-Amino-4-(2-naphthalenyl) thiazole (1) was prepared from 2-acetylnapthalene. This amine on facile condensation with aromatic aldehydes afford Schiff Base/anils/azomethines(2a-h). These anils on cyclocondensation reaction with chloro acetyl chloride and thio glycolic acid (i.e. mercapto acetic acid)...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2006/787638 |
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| _version_ | 1832554838886449152 |
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| author | K. H. Patel A. G. Mehta |
| author_facet | K. H. Patel A. G. Mehta |
| author_sort | K. H. Patel |
| collection | DOAJ |
| description | 2-Amino-4-(2-naphthalenyl) thiazole (1) was prepared from 2-acetylnapthalene. This amine on facile condensation with aromatic aldehydes afford Schiff Base/anils/azomethines(2a-h). These anils on cyclocondensation reaction with chloro acetyl chloride and thio glycolic acid (i.e. mercapto acetic acid) yields 2-azetidinones and 4-thiazolidinones respectively. The prepared compounds have been screened on some stains of bacteria. |
| format | Article |
| id | doaj-art-63792c3661ce4dfebdec8f49808f302f |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-63792c3661ce4dfebdec8f49808f302f2025-02-03T05:50:20ZengWileyE-Journal of Chemistry0973-49452090-98102006-01-013210310910.1155/2006/787638Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial EfficacyK. H. Patel0A. G. Mehta1Department of Chemistry, P.T.Science College, Surat, Gujarat, IndiaDepartment of Chemistry, P.T.Science College, Surat, Gujarat, India2-Amino-4-(2-naphthalenyl) thiazole (1) was prepared from 2-acetylnapthalene. This amine on facile condensation with aromatic aldehydes afford Schiff Base/anils/azomethines(2a-h). These anils on cyclocondensation reaction with chloro acetyl chloride and thio glycolic acid (i.e. mercapto acetic acid) yields 2-azetidinones and 4-thiazolidinones respectively. The prepared compounds have been screened on some stains of bacteria.http://dx.doi.org/10.1155/2006/787638 |
| spellingShingle | K. H. Patel A. G. Mehta Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy E-Journal of Chemistry |
| title | Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy |
| title_full | Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy |
| title_fullStr | Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy |
| title_full_unstemmed | Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy |
| title_short | Synthesis of Novel Azetidinone and Thiazolidinones Derivatives and Evaluation of Their Antimicrobial Efficacy |
| title_sort | synthesis of novel azetidinone and thiazolidinones derivatives and evaluation of their antimicrobial efficacy |
| url | http://dx.doi.org/10.1155/2006/787638 |
| work_keys_str_mv | AT khpatel synthesisofnovelazetidinoneandthiazolidinonesderivativesandevaluationoftheirantimicrobialefficacy AT agmehta synthesisofnovelazetidinoneandthiazolidinonesderivativesandevaluationoftheirantimicrobialefficacy |