Dual S-100-AE1/3 Immunohistochemistry to Detect Perineural Invasion in Nonmelanoma Skin Cancers

Background. Perineural invasion (PNI) is an adverse prognostic histologic finding and increases the risk of local recurrence and metastasis. Objective. We aimed to determine if dual immunohistochemical (IHC) staining with S-100 and AE1/3 would increase the detection of PNI on nonmelanoma skin cancer...

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Bibliographic Details
Main Authors: Alma C. Berlingeri-Ramos, Claire J. Detweiler, Richard F. Wagner, Brent C. Kelly
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2015/620235
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