Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing
In the field of whole slide imaging, the imaging device or staining process cause color variations for each slide that affect the result of image analysis made by pathologist. In order to stabilize the analysis, we developed a color standardization method and system as described below: 1) Color stan...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-2011-0037 |
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| _version_ | 1832556274416353280 |
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| author | Shinsuke Tani Yasuhiro Fukunaga Saori Shimizu Munenori Fukunishi Kensuke Ishii Kosei Tamiya |
| author_facet | Shinsuke Tani Yasuhiro Fukunaga Saori Shimizu Munenori Fukunishi Kensuke Ishii Kosei Tamiya |
| author_sort | Shinsuke Tani |
| collection | DOAJ |
| description | In the field of whole slide imaging, the imaging device or staining process cause color variations for each slide that affect the result of image analysis made by pathologist. In order to stabilize the analysis, we developed a color standardization method and system as described below: 1) Color standardization method based on RGB imaging and multi spectral sensing, which utilize less band (16 bands) than conventional method (60 bands), 2) High speed spectral sensing module. As a result, we confirmed the following effect: 1) We confirmed the performance improvement of nucleus detection by the color standardization. And we can conduct without training data set which is needed in conventional method, 2) We can get detection performance of H&E component equivalent to conventional method (60 bands). And measurement process is more than 255 times faster. |
| format | Article |
| id | doaj-art-63705f905dc94c05b1d9c698de463e1f |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-63705f905dc94c05b1d9c698de463e1f2025-02-03T05:45:48ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-0135210711510.3233/ACP-2011-0037Color Standardization Method and System for Whole Slide Imaging Based on Spectral SensingShinsuke Tani0Yasuhiro Fukunaga1Saori Shimizu2Munenori Fukunishi3Kensuke Ishii4Kosei Tamiya5Olympus Corporation, Imaging Technology Department, Hachioji-shi, Tokyo, JapanOlympus Corporation, Imager & Analog LSI Department, Hachioji, Tokyo, JapanOlympus Corporation, Imaging Technology Department, Hachioji-shi, Tokyo, JapanOlympus Corporation of Americas New Business Research & Development, Tokyo, JapanOlympus Corporation of Americas New Business Research & Development, Tokyo, JapanOlympus Corporation, Imager & Analog LSI Department, Hachioji, Tokyo, JapanIn the field of whole slide imaging, the imaging device or staining process cause color variations for each slide that affect the result of image analysis made by pathologist. In order to stabilize the analysis, we developed a color standardization method and system as described below: 1) Color standardization method based on RGB imaging and multi spectral sensing, which utilize less band (16 bands) than conventional method (60 bands), 2) High speed spectral sensing module. As a result, we confirmed the following effect: 1) We confirmed the performance improvement of nucleus detection by the color standardization. And we can conduct without training data set which is needed in conventional method, 2) We can get detection performance of H&E component equivalent to conventional method (60 bands). And measurement process is more than 255 times faster.http://dx.doi.org/10.3233/ACP-2011-0037 |
| spellingShingle | Shinsuke Tani Yasuhiro Fukunaga Saori Shimizu Munenori Fukunishi Kensuke Ishii Kosei Tamiya Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing Analytical Cellular Pathology |
| title | Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing |
| title_full | Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing |
| title_fullStr | Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing |
| title_full_unstemmed | Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing |
| title_short | Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing |
| title_sort | color standardization method and system for whole slide imaging based on spectral sensing |
| url | http://dx.doi.org/10.3233/ACP-2011-0037 |
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