Lipedema: exploring pathophysiology and treatment strategies – state of the art
Abstract Lipedema is characterized by abnormal fat deposition in areas such as the arms, hips, buttocks, and thighs, sparing the hands and feet. Symptoms include pain, bruising, edema, and subcutaneous nodules, which resist traditional interventions such as diet and exercise. Despite increasing reco...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
2025-01-01
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| Series: | Jornal Vascular Brasileiro |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492024000100405&lng=en&tlng=en |
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| author | Fabio Kamamoto Jaqueline Munaretto Timm Baiocchi Bernardo Nogueira Batista Renan Diego Américo Ribeiro Débora Aparecida Oliveira Modena Vitor Cervantes Gornati |
| author_facet | Fabio Kamamoto Jaqueline Munaretto Timm Baiocchi Bernardo Nogueira Batista Renan Diego Américo Ribeiro Débora Aparecida Oliveira Modena Vitor Cervantes Gornati |
| author_sort | Fabio Kamamoto |
| collection | DOAJ |
| description | Abstract Lipedema is characterized by abnormal fat deposition in areas such as the arms, hips, buttocks, and thighs, sparing the hands and feet. Symptoms include pain, bruising, edema, and subcutaneous nodules, which resist traditional interventions such as diet and exercise. Despite increasing recognition, comprehensive understanding, including pathophysiological, clinical, and therapeutic aspects, has not been fully achieved. This review aims to fill gaps in knowledge of this field, to support more informed management of lipedema. This narrative review provides a deeper understanding of lipedema treatment, addressing pathophysiology and therapeutic options. The data reveal advances in knowledge, especially regarding conservative and surgical treatments, focusing on improving quality of life. However, scientific evidence supporting the safety and efficacy of various treatments is lacking. Additional research is needed to ensure safety and to enhance efficacy of management of this complex condition. |
| format | Article |
| id | doaj-art-636d92f5bc9845a593e526bb8b0616b3 |
| institution | Kabale University |
| issn | 1677-7301 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) |
| record_format | Article |
| series | Jornal Vascular Brasileiro |
| spelling | doaj-art-636d92f5bc9845a593e526bb8b0616b32025-01-21T07:42:00ZengSociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)Jornal Vascular Brasileiro1677-73012025-01-012310.1590/1677-5449.202400252Lipedema: exploring pathophysiology and treatment strategies – state of the artFabio KamamotoJaqueline Munaretto Timm Baiocchihttps://orcid.org/0000-0001-5477-1634Bernardo Nogueira BatistaRenan Diego Américo RibeiroDébora Aparecida Oliveira Modenahttps://orcid.org/0000-0002-2800-3620Vitor Cervantes Gornatihttps://orcid.org/0000-0001-8460-0027Abstract Lipedema is characterized by abnormal fat deposition in areas such as the arms, hips, buttocks, and thighs, sparing the hands and feet. Symptoms include pain, bruising, edema, and subcutaneous nodules, which resist traditional interventions such as diet and exercise. Despite increasing recognition, comprehensive understanding, including pathophysiological, clinical, and therapeutic aspects, has not been fully achieved. This review aims to fill gaps in knowledge of this field, to support more informed management of lipedema. This narrative review provides a deeper understanding of lipedema treatment, addressing pathophysiology and therapeutic options. The data reveal advances in knowledge, especially regarding conservative and surgical treatments, focusing on improving quality of life. However, scientific evidence supporting the safety and efficacy of various treatments is lacking. Additional research is needed to ensure safety and to enhance efficacy of management of this complex condition.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492024000100405&lng=en&tlng=enlipedemalipolymphedemalipodystrophyadipose tissue dysfunctionabnormal fat deposits |
| spellingShingle | Fabio Kamamoto Jaqueline Munaretto Timm Baiocchi Bernardo Nogueira Batista Renan Diego Américo Ribeiro Débora Aparecida Oliveira Modena Vitor Cervantes Gornati Lipedema: exploring pathophysiology and treatment strategies – state of the art Jornal Vascular Brasileiro lipedema lipolymphedema lipodystrophy adipose tissue dysfunction abnormal fat deposits |
| title | Lipedema: exploring pathophysiology and treatment strategies – state of the art |
| title_full | Lipedema: exploring pathophysiology and treatment strategies – state of the art |
| title_fullStr | Lipedema: exploring pathophysiology and treatment strategies – state of the art |
| title_full_unstemmed | Lipedema: exploring pathophysiology and treatment strategies – state of the art |
| title_short | Lipedema: exploring pathophysiology and treatment strategies – state of the art |
| title_sort | lipedema exploring pathophysiology and treatment strategies state of the art |
| topic | lipedema lipolymphedema lipodystrophy adipose tissue dysfunction abnormal fat deposits |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492024000100405&lng=en&tlng=en |
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