Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy

A 41-year-old man with an unremarkable medical history presented with a painful knee after a sports injury. He was diagnosed with a medial meniscal tear. Symptoms did not abate after 6 months of physical therapy, and he underwent arthroscopic partial medial meniscectomy. A week after beginning physi...

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Main Authors: John E. Zvijac, Sharhabil S. Ammus, Fernando Aran, Gary M. Kiebzak
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2015/127846
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author John E. Zvijac
Sharhabil S. Ammus
Fernando Aran
Gary M. Kiebzak
author_facet John E. Zvijac
Sharhabil S. Ammus
Fernando Aran
Gary M. Kiebzak
author_sort John E. Zvijac
collection DOAJ
description A 41-year-old man with an unremarkable medical history presented with a painful knee after a sports injury. He was diagnosed with a medial meniscal tear. Symptoms did not abate after 6 months of physical therapy, and he underwent arthroscopic partial medial meniscectomy. A week after beginning physical therapy he experienced a knee effusion, decreased ROM, and inability to flex his quadriceps. His knee was aspirated. Blood tests were ordered and his complete blood count, liver functions tests, and INR/PTT were normal. The patient had recurrent effusions requiring three additional joint aspirations. Ten weeks after the initial surgery, the patient underwent a second arthroscopy, during which a hematoma was removed and a synovectomy performed. The patient continued bleeding from the incisions after portals were sutured, and he was admitted to the hospital. A hematologist was consulted and comprehensive platelet aggregation testing revealed previously undiagnosed Glanzmann’s thrombasthenia. The patient began treatment with platelet infusions and desmopressin and progressed to a full recovery. Clinical suspicion for surgical patients with unusual repetitive postoperative bleeding should include previously undetected rare bleeding disorders even in adults.
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spelling doaj-art-636cd54f3dd4463e8b2a56bc995ff1042025-02-03T00:59:28ZengWileyCase Reports in Orthopedics2090-67492090-67572015-01-01201510.1155/2015/127846127846Glanzmann’s Thrombasthenia Diagnosed following Knee ArthroscopyJohn E. Zvijac0Sharhabil S. Ammus1Fernando Aran2Gary M. Kiebzak3UHZ Sports Medicine Institute, Doctors Hospital, Baptist Health South Florida, 1150 Campo Sano Avenue, Suite 200, Coral Gables, FL 33146, USAUM Sylvester Cancer Center at Kendall, 8932 SW 97 Avenue, Suite B12, Miami, FL 33176, USAFIU Herbert Wertheim College of Medicine, Miami, FL 33199, USACenter for Research and Grants, Doctors Hospital, Baptist Health South Florida, 1150 Campo Sano Avenue, Suite 200, Coral Gables, FL 33146, USAA 41-year-old man with an unremarkable medical history presented with a painful knee after a sports injury. He was diagnosed with a medial meniscal tear. Symptoms did not abate after 6 months of physical therapy, and he underwent arthroscopic partial medial meniscectomy. A week after beginning physical therapy he experienced a knee effusion, decreased ROM, and inability to flex his quadriceps. His knee was aspirated. Blood tests were ordered and his complete blood count, liver functions tests, and INR/PTT were normal. The patient had recurrent effusions requiring three additional joint aspirations. Ten weeks after the initial surgery, the patient underwent a second arthroscopy, during which a hematoma was removed and a synovectomy performed. The patient continued bleeding from the incisions after portals were sutured, and he was admitted to the hospital. A hematologist was consulted and comprehensive platelet aggregation testing revealed previously undiagnosed Glanzmann’s thrombasthenia. The patient began treatment with platelet infusions and desmopressin and progressed to a full recovery. Clinical suspicion for surgical patients with unusual repetitive postoperative bleeding should include previously undetected rare bleeding disorders even in adults.http://dx.doi.org/10.1155/2015/127846
spellingShingle John E. Zvijac
Sharhabil S. Ammus
Fernando Aran
Gary M. Kiebzak
Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy
Case Reports in Orthopedics
title Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy
title_full Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy
title_fullStr Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy
title_full_unstemmed Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy
title_short Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy
title_sort glanzmann s thrombasthenia diagnosed following knee arthroscopy
url http://dx.doi.org/10.1155/2015/127846
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AT fernandoaran glanzmannsthrombastheniadiagnosedfollowingkneearthroscopy
AT garymkiebzak glanzmannsthrombastheniadiagnosedfollowingkneearthroscopy