Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early puberty

Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early puberty

ObjectiveIt can be challenging to determine the correct dosage of recombinant growth hormone (GH) in children with GH deficiency, leading to highly variable treatment responses. Insulin-like growth factor-1 (IGF-1) is a tool for monitoring GH treatment and dosing. However, IGF-1 levels depend on sex...

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Bibliographic Details
Main Authors:	Helena-Jamin Ly, Carina Ankarberg-Lindgren, Hans Fors, Staffan Nilsson, Jovanna Dahlgren
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Endocrinology
Subjects:	growth hormone dosing growth hormone treatment insulin-like growth factor-1 pubertal signs sex steroid
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1514935/full
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