Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour
A gradient coating containing collagen and inorganic strontium/calcium phosphate (Sr/CaP) was fabricated on plasma-electrolytically oxidised magnesium via one-step cathodic electrodeposition. First, Sr-doped dicalcium phosphate dihydrate and hydroxyapatite (DCPD and HA) was deposited, followed by a...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2025-01-01
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| Series: | Journal of Magnesium and Alloys |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213956724001956 |
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| author | Jiaping Han Kai Fu Zhiqiang Jiang Hao Zhang Hongshan San Hui Chen Xiaopeng Lu Carsten Blawert Mikhail.L. Zheludkevich |
| author_facet | Jiaping Han Kai Fu Zhiqiang Jiang Hao Zhang Hongshan San Hui Chen Xiaopeng Lu Carsten Blawert Mikhail.L. Zheludkevich |
| author_sort | Jiaping Han |
| collection | DOAJ |
| description | A gradient coating containing collagen and inorganic strontium/calcium phosphate (Sr/CaP) was fabricated on plasma-electrolytically oxidised magnesium via one-step cathodic electrodeposition. First, Sr-doped dicalcium phosphate dihydrate and hydroxyapatite (DCPD and HA) was deposited, followed by a collagen/CaP layer. The morphological evolution, sequential degradation behaviour, and in vitro bio-properties of the coatings were investigated. The incorporation of collagen remarkably refined the morphology of the CaP, and a more aggregated nano-spherical morphology was observed with increasing collagen concentration. Sr could partially replace Ca in the CaP crystals. Collagen combined with CaP formed a relatively stable skeletal frame, which provided sufficient barrier properties and more sites for the re-precipitation of bone tissue, as well as a more promising proliferation and differentiation ability of osteoblasts. A gradient coating that matches the requirements of bone growth at various periods is suggested for implantation. |
| format | Article |
| id | doaj-art-636b848544b8467bbef363651ccbd856 |
| institution | Kabale University |
| issn | 2213-9567 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Magnesium and Alloys |
| spelling | doaj-art-636b848544b8467bbef363651ccbd8562025-02-06T05:11:41ZengKeAi Communications Co., Ltd.Journal of Magnesium and Alloys2213-95672025-01-01131356378Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviourJiaping Han0Kai Fu1Zhiqiang Jiang2Hao Zhang3Hongshan San4Hui Chen5Xiaopeng Lu6Carsten Blawert7Mikhail.L. Zheludkevich8Institute of Vanadium and Titanium, Panzhihua University, PanZhiHua 617000, PR China; School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China; Corresponding authors.Institute of Vanadium and Titanium, Panzhihua University, PanZhiHua 617000, PR ChinaInstitute of Vanadium and Titanium, Panzhihua University, PanZhiHua 617000, PR ChinaInstitute of Vanadium and Titanium, Panzhihua University, PanZhiHua 617000, PR ChinaSchool of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo 454003, PR China; Corresponding authors.School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China; Corresponding authors.Shenyang National Laboratory for Materials Science, Northeastern University, 3-11 Wenhua Road, Shenyang 110819, PR China; Corresponding authors.Institute of Surface Science, Helmholtz-Zentrum Hereon, Geesthacht 21502, GermanyInstitute of Surface Science, Helmholtz-Zentrum Hereon, Geesthacht 21502, GermanyA gradient coating containing collagen and inorganic strontium/calcium phosphate (Sr/CaP) was fabricated on plasma-electrolytically oxidised magnesium via one-step cathodic electrodeposition. First, Sr-doped dicalcium phosphate dihydrate and hydroxyapatite (DCPD and HA) was deposited, followed by a collagen/CaP layer. The morphological evolution, sequential degradation behaviour, and in vitro bio-properties of the coatings were investigated. The incorporation of collagen remarkably refined the morphology of the CaP, and a more aggregated nano-spherical morphology was observed with increasing collagen concentration. Sr could partially replace Ca in the CaP crystals. Collagen combined with CaP formed a relatively stable skeletal frame, which provided sufficient barrier properties and more sites for the re-precipitation of bone tissue, as well as a more promising proliferation and differentiation ability of osteoblasts. A gradient coating that matches the requirements of bone growth at various periods is suggested for implantation.http://www.sciencedirect.com/science/article/pii/S2213956724001956Biomedical magnesium alloysGradient coatingSequential degradationBarrier propertyBone formationBiocompatibility |
| spellingShingle | Jiaping Han Kai Fu Zhiqiang Jiang Hao Zhang Hongshan San Hui Chen Xiaopeng Lu Carsten Blawert Mikhail.L. Zheludkevich Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour Journal of Magnesium and Alloys Biomedical magnesium alloys Gradient coating Sequential degradation Barrier property Bone formation Biocompatibility |
| title | Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour |
| title_full | Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour |
| title_fullStr | Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour |
| title_full_unstemmed | Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour |
| title_short | Smart gradient coating suitable for bone growth prepared on plasma-electrolytically oxidised Mg and its sequential degradation behaviour |
| title_sort | smart gradient coating suitable for bone growth prepared on plasma electrolytically oxidised mg and its sequential degradation behaviour |
| topic | Biomedical magnesium alloys Gradient coating Sequential degradation Barrier property Bone formation Biocompatibility |
| url | http://www.sciencedirect.com/science/article/pii/S2213956724001956 |
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