Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy

Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy

Abstract Healthy blood vessels supply neurons to preserve metabolic function. In blinding proliferative retinopathies (PRs), pathological neovascular tufts often emerge in lieu of needed physiological revascularization. Here we show that metabolic shifts in the neovascular niche define angiogenic fa...

Full description

Saved in:
Bibliographic Details
Main Authors: Gael Cagnone, Sheetal Pundir, Charlotte Betus, Tapan Agnihotri, Anli Ren, Jin Sung -Kim, Noémie-Rose Harvey, Emilie Heckel, Mei Xi Chen, Anu Situ, Perrine Gaub, Nicholas Kim, Ashim Das, Severine Leclerc, Florian Wünnemann, Louis Berillon, Gregor Andelfinger, Sergio Crespo-Garcia, Alexandre Dubrac, Flavio A. Rezende, Clary B. Clish, Bruno Maranda, José Carlos Rivera, Lois E. H. Smith, Przemyslaw Sapieha, Jean-Sébastien Joyal
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60061-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items