Human parietal epithelial cells as Trojan horses in albumin overload

Human parietal epithelial cells as Trojan horses in albumin overload

Abstract Parietal Epithelial Cells (PECs) activation and proliferation are common to several distinct forms of glomerulopathies. Due to several stimuli, PECs can change to a progenitor (CD24+ and CD133/2+) or a pro-sclerotic (CD44+) phenotype. In addition, PECs, which are constantly exposed to filte...

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Main Authors: Giovanna Priante, Monica Ceol, Lisa Gianesello, Claudia Maria Radu, Rachele Mantese, Lucia Federica Stefanelli, Martina Cacciapuoti, Francesca K. Martino, Lorenzo Arcangelo Calò, Franca Anglani, Federico Nalesso, Dorella Del Prete
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
hPECs
Albumin
ClC-5
Megalin
Cubilin
CD44
Online Access:https://doi.org/10.1038/s41598-024-84972-2
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https://doi.org/10.1038/s41598-024-84972-2

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