Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21
Congenital cytomegalovirus infection (cCMV) is very common, yet the presentation can be varied, making the diagnosis challenging. However, early diagnosis for treatment with medication in symptomatic cases within the first month of life is critical. Hyperbilirubinemia and splenomegaly are less commo...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2020/2534629 |
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| _version_ | 1832547706223984640 |
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| author | Kate Wilson Lindsay Ellsworth Megan H. Pesch |
| author_facet | Kate Wilson Lindsay Ellsworth Megan H. Pesch |
| author_sort | Kate Wilson |
| collection | DOAJ |
| description | Congenital cytomegalovirus infection (cCMV) is very common, yet the presentation can be varied, making the diagnosis challenging. However, early diagnosis for treatment with medication in symptomatic cases within the first month of life is critical. Hyperbilirubinemia and splenomegaly are less common manifestations at birth and may be overlooked in the setting of other symptoms, especially in a critically ill neonate. We present a case of a term infant with trisomy 21 who presented with isolated hyperbilirubinemia and splenomegaly and was later diagnosed with congenital CMV. |
| format | Article |
| id | doaj-art-6325edac36504e1cb457b5b97a58fbbe |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-6325edac36504e1cb457b5b97a58fbbe2025-02-03T06:43:40ZengWileyCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/25346292534629Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21Kate Wilson0Lindsay Ellsworth1Megan H. Pesch2Division of Neonatal Perinatal Medicine, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USADivision of Neonatal Perinatal Medicine, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USADivision of Developmental and Behavioral Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USACongenital cytomegalovirus infection (cCMV) is very common, yet the presentation can be varied, making the diagnosis challenging. However, early diagnosis for treatment with medication in symptomatic cases within the first month of life is critical. Hyperbilirubinemia and splenomegaly are less common manifestations at birth and may be overlooked in the setting of other symptoms, especially in a critically ill neonate. We present a case of a term infant with trisomy 21 who presented with isolated hyperbilirubinemia and splenomegaly and was later diagnosed with congenital CMV.http://dx.doi.org/10.1155/2020/2534629 |
| spellingShingle | Kate Wilson Lindsay Ellsworth Megan H. Pesch Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21 Case Reports in Pediatrics |
| title | Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21 |
| title_full | Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21 |
| title_fullStr | Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21 |
| title_full_unstemmed | Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21 |
| title_short | Congenital Cytomegalovirus Infection Presenting with Hyperbilirubinemia and Splenomegaly in a Term Infant with Trisomy 21 |
| title_sort | congenital cytomegalovirus infection presenting with hyperbilirubinemia and splenomegaly in a term infant with trisomy 21 |
| url | http://dx.doi.org/10.1155/2020/2534629 |
| work_keys_str_mv | AT katewilson congenitalcytomegalovirusinfectionpresentingwithhyperbilirubinemiaandsplenomegalyinaterminfantwithtrisomy21 AT lindsayellsworth congenitalcytomegalovirusinfectionpresentingwithhyperbilirubinemiaandsplenomegalyinaterminfantwithtrisomy21 AT meganhpesch congenitalcytomegalovirusinfectionpresentingwithhyperbilirubinemiaandsplenomegalyinaterminfantwithtrisomy21 |