Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses

Rationale and objectives: To evaluate the impact of low dose-low contrast medium injection protocol on radiation dose and image quality of one-stop dual source high pitch integrated coronary -carotid -cerebral- aortic CTA. Methods: A total of 211 non-obese patients, consisting of 44 females with an...

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Main Authors: Meng Wang, Chao Zheng, Lin Yang, Juan Su, Bo Wang, JieXin Sheng
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:European Journal of Radiology Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352047725000048
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author Meng Wang
Chao Zheng
Lin Yang
Juan Su
Bo Wang
JieXin Sheng
author_facet Meng Wang
Chao Zheng
Lin Yang
Juan Su
Bo Wang
JieXin Sheng
author_sort Meng Wang
collection DOAJ
description Rationale and objectives: To evaluate the impact of low dose-low contrast medium injection protocol on radiation dose and image quality of one-stop dual source high pitch integrated coronary -carotid -cerebral- aortic CTA. Methods: A total of 211 non-obese patients, consisting of 44 females with an average age of 59 years, were split into two groups: low dose group (LD group n = 136) and routine dose group (RD group n = 75). Noise, attenuation, signal to noise ratio (SNR), and contrast to noise ratio (CNR) were compared between the groups by setting region of interest (ROI) in target vessels to evaluate objective image quality. Two radiologists assessed subjective image quality using the 5-point scale. volumetric CT dose index (CTDIvol), dose length production (DLP), and effective radiation dose (ED) were compared, while contrast medium (CM) dose was assessed by CM volume and iodine uptake (IU). Results: Both radiation and CM dose were significantly reduced in the LD group compared with the RD group, DLP and ED were reduced by 51 %, and CM volume and IU were reduced by 13 % (all p < 0.05). Attenuation and noise were higher, while SNR and CNR were close to or slightly higher in the LD group compared with the RD group. The LD group had higher subjective image quality scores while all scores in the two groups satisfied the diagnostic requirements. Conclusion: Low-kV, low-CM one-stop dual-source high-pitch integrated coronary-carotid-cerebral-aortic CTA can ensure image quality while significantly reducing the doses of contrast medium and radiation
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institution Kabale University
issn 2352-0477
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publishDate 2025-06-01
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spelling doaj-art-62fbe391cda345888627490819dbccd52025-01-30T05:14:22ZengElsevierEuropean Journal of Radiology Open2352-04772025-06-0114100637Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium dosesMeng Wang0Chao Zheng1Lin Yang2Juan Su3Bo Wang4JieXin Sheng5Department of Radiology, Hanzhong Central Hospital, Hanzhong City, Shannxi Province, ChinaDepartment of Radiology, Hanzhong Central Hospital, Hanzhong City, Shannxi Province, ChinaDepartment of Radiology, Hanzhong Central Hospital, Hanzhong City, Shannxi Province, ChinaDepartment of Radiology, Hanzhong Central Hospital, Hanzhong City, Shannxi Province, ChinaDepartment of Radiology, Hanzhong Central Hospital, Hanzhong City, Shannxi Province, ChinaCorrespondence to: Hanzhong Central Hospital, 22 Kang Fu Road, Hanzhong City, Shannxi Province 723000, China.; Department of Radiology, Hanzhong Central Hospital, Hanzhong City, Shannxi Province, ChinaRationale and objectives: To evaluate the impact of low dose-low contrast medium injection protocol on radiation dose and image quality of one-stop dual source high pitch integrated coronary -carotid -cerebral- aortic CTA. Methods: A total of 211 non-obese patients, consisting of 44 females with an average age of 59 years, were split into two groups: low dose group (LD group n = 136) and routine dose group (RD group n = 75). Noise, attenuation, signal to noise ratio (SNR), and contrast to noise ratio (CNR) were compared between the groups by setting region of interest (ROI) in target vessels to evaluate objective image quality. Two radiologists assessed subjective image quality using the 5-point scale. volumetric CT dose index (CTDIvol), dose length production (DLP), and effective radiation dose (ED) were compared, while contrast medium (CM) dose was assessed by CM volume and iodine uptake (IU). Results: Both radiation and CM dose were significantly reduced in the LD group compared with the RD group, DLP and ED were reduced by 51 %, and CM volume and IU were reduced by 13 % (all p < 0.05). Attenuation and noise were higher, while SNR and CNR were close to or slightly higher in the LD group compared with the RD group. The LD group had higher subjective image quality scores while all scores in the two groups satisfied the diagnostic requirements. Conclusion: Low-kV, low-CM one-stop dual-source high-pitch integrated coronary-carotid-cerebral-aortic CTA can ensure image quality while significantly reducing the doses of contrast medium and radiationhttp://www.sciencedirect.com/science/article/pii/S2352047725000048Dual-source CTHigh pitchOne-stopCT angiographyLow dose
spellingShingle Meng Wang
Chao Zheng
Lin Yang
Juan Su
Bo Wang
JieXin Sheng
Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses
European Journal of Radiology Open
Dual-source CT
High pitch
One-stop
CT angiography
Low dose
title Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses
title_full Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses
title_fullStr Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses
title_full_unstemmed Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses
title_short Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses
title_sort low kv low contrast medium dose one stop dual source ct high pitch integrated coronary carotid cerebral aortic cta improves image quality and reduces both radiation and contrast medium doses
topic Dual-source CT
High pitch
One-stop
CT angiography
Low dose
url http://www.sciencedirect.com/science/article/pii/S2352047725000048
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