Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era
Objectives. To identify rates of incidentally detected prostate cancer in patients undergoing surgical management of benign prostatic hyperplasia (BPH). Materials and Methods. A retrospective review was performed on all transurethral resections of the prostate (TURP) regardless of technique from 20...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Advances in Urology |
| Online Access: | http://dx.doi.org/10.1155/2014/627290 |
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| _version_ | 1832555050442948608 |
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| author | Brandon Otto Christopher Barbieri Richard Lee Alexis E. Te Steven A. Kaplan Brian Robinson Bilal Chughtai |
| author_facet | Brandon Otto Christopher Barbieri Richard Lee Alexis E. Te Steven A. Kaplan Brian Robinson Bilal Chughtai |
| author_sort | Brandon Otto |
| collection | DOAJ |
| description | Objectives. To identify rates of incidentally detected prostate cancer in patients undergoing surgical management of benign prostatic hyperplasia (BPH).
Materials and Methods. A retrospective review was performed on all transurethral resections of the prostate (TURP) regardless of technique from 2006 to 2011 at a single tertiary care institution. 793 men (ages 45–90) were identified by pathology specimen. Those with a known diagnosis of prostate cancer prior to TURP were excluded (n=22) from the analysis. Results. 760 patients had benign pathology; eleven (1.4%) patients were found to have prostate cancer. Grade of disease ranged from Gleason 3+3=6 to Gleason 3+4=7. Nine patients had cT1a disease and two had cT1b disease. Seven patients were managed by active surveillance with no further events, one patient underwent radiation, and three patients underwent radical prostatectomy. Conclusions. Our series demonstrates that 1.4% of patients were found to have prostate cancer, of these 0.5% required treatment. Given the low incidental prostate cancer detection rate, the value of pathologic review of TURP specimens may be limited depending on the patient population. |
| format | Article |
| id | doaj-art-62ccc27be4dc4fc68eb2a7ddf1e2ee40 |
| institution | Kabale University |
| issn | 1687-6369 1687-6377 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Urology |
| spelling | doaj-art-62ccc27be4dc4fc68eb2a7ddf1e2ee402025-02-03T05:49:44ZengWileyAdvances in Urology1687-63691687-63772014-01-01201410.1155/2014/627290627290Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern EraBrandon Otto0Christopher Barbieri1Richard Lee2Alexis E. Te3Steven A. Kaplan4Brian Robinson5Bilal Chughtai6Department of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USADepartment of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USADepartment of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USADepartment of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USADepartment of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USADepartment of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USADepartment of Urology, Weill Medical College of Cornell University, New York-Presbyterian Hospital, 425 E 61st Street, New York, NY 10065, USAObjectives. To identify rates of incidentally detected prostate cancer in patients undergoing surgical management of benign prostatic hyperplasia (BPH). Materials and Methods. A retrospective review was performed on all transurethral resections of the prostate (TURP) regardless of technique from 2006 to 2011 at a single tertiary care institution. 793 men (ages 45–90) were identified by pathology specimen. Those with a known diagnosis of prostate cancer prior to TURP were excluded (n=22) from the analysis. Results. 760 patients had benign pathology; eleven (1.4%) patients were found to have prostate cancer. Grade of disease ranged from Gleason 3+3=6 to Gleason 3+4=7. Nine patients had cT1a disease and two had cT1b disease. Seven patients were managed by active surveillance with no further events, one patient underwent radiation, and three patients underwent radical prostatectomy. Conclusions. Our series demonstrates that 1.4% of patients were found to have prostate cancer, of these 0.5% required treatment. Given the low incidental prostate cancer detection rate, the value of pathologic review of TURP specimens may be limited depending on the patient population.http://dx.doi.org/10.1155/2014/627290 |
| spellingShingle | Brandon Otto Christopher Barbieri Richard Lee Alexis E. Te Steven A. Kaplan Brian Robinson Bilal Chughtai Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era Advances in Urology |
| title | Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era |
| title_full | Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era |
| title_fullStr | Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era |
| title_full_unstemmed | Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era |
| title_short | Incidental Prostate Cancer in Transurethral Resection of the Prostate Specimens in the Modern Era |
| title_sort | incidental prostate cancer in transurethral resection of the prostate specimens in the modern era |
| url | http://dx.doi.org/10.1155/2014/627290 |
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