Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS)
Introduction Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation and outcome comparison across studies. This limitation can be reversed by developing a core measurement set (CMS) for DCM research. Previously, the AO...
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e060436.full |
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| author | Robert Chen Angus G K McNair Vafa Rahimi-Movaghar Julio C Furlan Benjamin M Davies Oliver D Mowforth Iwan Sadler Bizhan Aarabi Brian K Kwon Michael G Fehlings James S Harrop Armin Curt Ellen Sarewitz Carl Moritz Zipser Timothy F Boerger Mark R N Kotter James Milligan Lindsay Tetreault Danyal Khan Keng Siang Lee Alvaro Yanez Touzet Ricardo Rodrigues-Pinto James D Guest Sukhvinder Kalsi-Ryan Shirley Widdop |
| author_facet | Robert Chen Angus G K McNair Vafa Rahimi-Movaghar Julio C Furlan Benjamin M Davies Oliver D Mowforth Iwan Sadler Bizhan Aarabi Brian K Kwon Michael G Fehlings James S Harrop Armin Curt Ellen Sarewitz Carl Moritz Zipser Timothy F Boerger Mark R N Kotter James Milligan Lindsay Tetreault Danyal Khan Keng Siang Lee Alvaro Yanez Touzet Ricardo Rodrigues-Pinto James D Guest Sukhvinder Kalsi-Ryan Shirley Widdop |
| author_sort | Robert Chen |
| collection | DOAJ |
| description | Introduction Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation and outcome comparison across studies. This limitation can be reversed by developing a core measurement set (CMS) for DCM research. Previously, the AO Spine Research Objectives and Common Data Elements for DCM (AO Spine RECODE-DCM) defined ‘what’ should be measured in DCM: the next step of this initiative is to determine ‘how’ to measure these features. This protocol outlines the steps necessary for the development of a CMS for DCM research and audit.Methods and analysis The CMS will be developed in accordance with the guidance developed by the Core Outcome Measures in Effectiveness Trials and the Consensus-based Standards for the selection of health Measurement Instruments. The process involves five phases. In phase 1, the steering committee agreed on the constructs to be measured by sourcing consensus definitions from patients, professionals and the literature. In phases 2 and 3, systematic reviews were conducted to identify tools for each construct and aggregate their evidence. Constructs with and without tools were identified, and scoping reviews were conducted for constructs without tools. Evidence on measurement properties, as well as on timing of assessments, are currently being aggregated. These will be presented in phase 4: a consensus meeting where a multi-disciplinary panel of experts will select the instruments that will form the CMS. Following selection, guidance on the implementation of the CMS will be developed and disseminated (phase 5). A preliminary CMS review scheduled at 4 years from release.Ethics and dissemination Ethical approval was obtained from the University of Cambridge (HBREC2019.14). Dissemination strategies will include peer-reviewed scientific publications; conference presentations; podcasts; the identification of AO Spine RECODE-DCM ambassadors; and engagement with relevant journals, funders and the DCM community. |
| format | Article |
| id | doaj-art-62ba7e4be2844eda93f6803fd07cfdd3 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-62ba7e4be2844eda93f6803fd07cfdd32025-01-24T07:35:11ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-060436Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS)Robert Chen0Angus G K McNair1Vafa Rahimi-Movaghar2Julio C Furlan3Benjamin M Davies4Oliver D Mowforth5Iwan Sadler6Bizhan Aarabi7Brian K Kwon8Michael G Fehlings9James S Harrop10Armin Curt11Ellen Sarewitz12Carl Moritz Zipser13Timothy F Boerger14Mark R N Kotter15James Milligan16Lindsay Tetreault17Danyal Khan18Keng Siang Lee19Alvaro Yanez Touzet20Ricardo Rodrigues-Pinto21James D Guest22Sukhvinder Kalsi-Ryan23Shirley Widdop24Neurology, Toronto Western Hospital, Toronto, Ontario, CanadaNorth Bristol NHS Trust, Bristol, UKAcademic Department of Neurological Surgery, Sina Trauma and Surgery Research Center, Tehran, IranDepartment of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto, Toronto, Ontario, CanadaDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, UKDepartment of Clinical Neurosurgery, University of Cambridge, Cambridge, UKMyelopathy.org, Cambridge, UKDivision of Neurosurgery, University of Maryland, Baltimore, Maryland, USADepartment of Orthopaedics, University of British Columbia, Blusson Spinal Cord Center, Vancouver, British Columbia, CanadaDivision of Neurosurgery and Spine Program, Department of Surgery, University of Toronto, Toronto, Ontario, CanadaDivision of Neurosurgery, Thomas Jefferson University Hospital, Jefferson Health System, St Louis, Mississippi, USAUniversity Hospital Balgrist, Zürich, SwitzerlandMyelopathy.org, Cambridge, UKDepartment of Neurology, University Hospital Balgrist, Zurich, SwitzerlandNeurosurgery, Medical College of Wisconsin, Wauwatosa, Wisconsin, USADepartment of Clinical Neurosurgery, University of Cambridge, Cambridge, UK7 CSL Seqirus, Maidenhead, UKDepartment of Surgery, University of Toronto, Toronto, Ontario, CanadaQueen Square Institute of Neurology, University College London, London, UKBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UKSchool of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, University of Manchester, Manchester, UKSpinal Unit (UVM), Department of Orthopaedics, Centro Hospitalar Universitário do Porto EPE, Porto, PortugalDepartment of Neurosurgery and The Miami Project to Cure Paralysis, The Miller School of Medicine, University of Miami, Miami, Florida, USAToronto Rehabilitation Institute, Toronto, Ontario, CanadaMyelopathy.org, Cambridge, UKIntroduction Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation and outcome comparison across studies. This limitation can be reversed by developing a core measurement set (CMS) for DCM research. Previously, the AO Spine Research Objectives and Common Data Elements for DCM (AO Spine RECODE-DCM) defined ‘what’ should be measured in DCM: the next step of this initiative is to determine ‘how’ to measure these features. This protocol outlines the steps necessary for the development of a CMS for DCM research and audit.Methods and analysis The CMS will be developed in accordance with the guidance developed by the Core Outcome Measures in Effectiveness Trials and the Consensus-based Standards for the selection of health Measurement Instruments. The process involves five phases. In phase 1, the steering committee agreed on the constructs to be measured by sourcing consensus definitions from patients, professionals and the literature. In phases 2 and 3, systematic reviews were conducted to identify tools for each construct and aggregate their evidence. Constructs with and without tools were identified, and scoping reviews were conducted for constructs without tools. Evidence on measurement properties, as well as on timing of assessments, are currently being aggregated. These will be presented in phase 4: a consensus meeting where a multi-disciplinary panel of experts will select the instruments that will form the CMS. Following selection, guidance on the implementation of the CMS will be developed and disseminated (phase 5). A preliminary CMS review scheduled at 4 years from release.Ethics and dissemination Ethical approval was obtained from the University of Cambridge (HBREC2019.14). Dissemination strategies will include peer-reviewed scientific publications; conference presentations; podcasts; the identification of AO Spine RECODE-DCM ambassadors; and engagement with relevant journals, funders and the DCM community.https://bmjopen.bmj.com/content/12/6/e060436.full |
| spellingShingle | Robert Chen Angus G K McNair Vafa Rahimi-Movaghar Julio C Furlan Benjamin M Davies Oliver D Mowforth Iwan Sadler Bizhan Aarabi Brian K Kwon Michael G Fehlings James S Harrop Armin Curt Ellen Sarewitz Carl Moritz Zipser Timothy F Boerger Mark R N Kotter James Milligan Lindsay Tetreault Danyal Khan Keng Siang Lee Alvaro Yanez Touzet Ricardo Rodrigues-Pinto James D Guest Sukhvinder Kalsi-Ryan Shirley Widdop Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) BMJ Open |
| title | Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) |
| title_full | Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) |
| title_fullStr | Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) |
| title_full_unstemmed | Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) |
| title_short | Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) |
| title_sort | development of a core measurement set for research in degenerative cervical myelopathy a study protocol ao spine recode dcm cms |
| url | https://bmjopen.bmj.com/content/12/6/e060436.full |
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