Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases

<b>Background</b>: Italy, particularly the northern region of Lombardy, has experienced very high rates of COVID-19 cases and deaths. Several indicators, i.e., the number of new positive cases, deaths and hospitalizations, have been used to monitor virus spread, but all suffer from biase...

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Main Authors: Daniele del Re, Luigi Palla, Paolo Meridiani, Livia Soffi, Michele Tancredi Loiudice, Martina Antinozzi, Maria Sofia Cattaruzza
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/2/181
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author Daniele del Re
Luigi Palla
Paolo Meridiani
Livia Soffi
Michele Tancredi Loiudice
Martina Antinozzi
Maria Sofia Cattaruzza
author_facet Daniele del Re
Luigi Palla
Paolo Meridiani
Livia Soffi
Michele Tancredi Loiudice
Martina Antinozzi
Maria Sofia Cattaruzza
author_sort Daniele del Re
collection DOAJ
description <b>Background</b>: Italy, particularly the northern region of Lombardy, has experienced very high rates of COVID-19 cases and deaths. Several indicators, i.e., the number of new positive cases, deaths and hospitalizations, have been used to monitor virus spread, but all suffer from biases. The aim of this study was to evaluate an alternative data source from Emergency Medical Service (EMS) activities for COVID-19 monitoring. <b>Methods</b>: Calls to the emergency number (112) in Lombardy (years 2015–2022) were studied and their overlap with the COVID-19 pandemic, influenza and official mortality peaks were evaluated. Modeling it as a counting process, a specific cause contribution (i.e., COVID-19 symptoms, the “signal”) was identified and enucleated from all other contributions (the “background”), and the latter was subtracted from the total observed number of calls using statistical methods for excess event estimation. <b>Results</b>: A total of 6,094,502 records were analyzed and filtered for respiratory and cardiological symptoms to identify potential COVID-19 patients, yielding 742,852 relevant records. Results show that EMS data mirrored the time series of cases or deaths in Lombardy, with good agreement also being found with seasonal flu outbreaks. <b>Conclusions</b>: This novel approach, combined with a machine learning predictive approach, could be a powerful public health tool to signal the start of disease outbreaks and monitor the spread of infectious diseases.
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spelling doaj-art-629b5bbd0ef34b2c9914dfa873b64ce82025-01-24T13:29:01ZengMDPI AGDiagnostics2075-44182025-01-0115218110.3390/diagnostics15020181Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious DiseasesDaniele del Re0Luigi Palla1Paolo Meridiani2Livia Soffi3Michele Tancredi Loiudice4Martina Antinozzi5Maria Sofia Cattaruzza6Department of Physics, Sapienza University of Rome, 00185 Rome, ItalyDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, ItalyINFN Istituto Nazionale Fisica Nucleare, Sezione di Roma, 00146 Rome, ItalyINFN Istituto Nazionale Fisica Nucleare, Sezione di Roma, 00146 Rome, ItalyDepartment of Developmental and Social Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, 00185 Rome, ItalyDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, ItalyDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy<b>Background</b>: Italy, particularly the northern region of Lombardy, has experienced very high rates of COVID-19 cases and deaths. Several indicators, i.e., the number of new positive cases, deaths and hospitalizations, have been used to monitor virus spread, but all suffer from biases. The aim of this study was to evaluate an alternative data source from Emergency Medical Service (EMS) activities for COVID-19 monitoring. <b>Methods</b>: Calls to the emergency number (112) in Lombardy (years 2015–2022) were studied and their overlap with the COVID-19 pandemic, influenza and official mortality peaks were evaluated. Modeling it as a counting process, a specific cause contribution (i.e., COVID-19 symptoms, the “signal”) was identified and enucleated from all other contributions (the “background”), and the latter was subtracted from the total observed number of calls using statistical methods for excess event estimation. <b>Results</b>: A total of 6,094,502 records were analyzed and filtered for respiratory and cardiological symptoms to identify potential COVID-19 patients, yielding 742,852 relevant records. Results show that EMS data mirrored the time series of cases or deaths in Lombardy, with good agreement also being found with seasonal flu outbreaks. <b>Conclusions</b>: This novel approach, combined with a machine learning predictive approach, could be a powerful public health tool to signal the start of disease outbreaks and monitor the spread of infectious diseases.https://www.mdpi.com/2075-4418/15/2/181COVID-19emergency medical servicespandemicexcess mortality estimationinfectious diseases
spellingShingle Daniele del Re
Luigi Palla
Paolo Meridiani
Livia Soffi
Michele Tancredi Loiudice
Martina Antinozzi
Maria Sofia Cattaruzza
Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases
Diagnostics
COVID-19
emergency medical services
pandemic
excess mortality estimation
infectious diseases
title Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases
title_full Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases
title_fullStr Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases
title_full_unstemmed Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases
title_short Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases
title_sort data from emergency medical service activities a novel approach to monitoring covid 19 and other infectious diseases
topic COVID-19
emergency medical services
pandemic
excess mortality estimation
infectious diseases
url https://www.mdpi.com/2075-4418/15/2/181
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