Zinc Acetate as a Cross-Linking Agent in the Development of Enteric Microcapsules for Posaconazole

Zinc Acetate as a Cross-Linking Agent in the Development of Enteric Microcapsules for Posaconazole

<b>Background/Objectives:</b> Posaconazole is an antifungal agent from triazoles with variable bioavailability. To avoid its irregular absorption caused by gastric conditions and ensure more repeatable pharmacokinetic enabling the maximization of its absorption regardless of food intake...

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Main Authors: Marta Szekalska, Giedrė Kasparavičienė, Jurga Bernatonienė, Eliza Wolska, Paweł Misiak, Karolina Halina Markiewicz, Agnieszka Zofia Wilczewska, Anna Czajkowska-Kośnik, Katarzyna Winnicka
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceutics
Subjects:
microcapsules
sodium alginate
pectin
posaconazole
cross-linking
co-extrusion
Online Access:https://www.mdpi.com/1999-4923/17/3/291
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