A Review of Mendelian Randomization: Assumptions, Methods, and Application to Obesity-Related Diseases
Mendelian randomization (MR) is a statistical method that uses genetic variants as instrumental variables to estimate the causal effect of exposure on an outcome in the presence of unmeasured confounding. In this review, we argue that it is crucial to acknowledge the instrumental variable assumption...
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Main Authors: | Seungjae Lee, Woojoo Lee |
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Format: | Article |
Language: | English |
Published: |
Korean Society for the Study of Obesity
2025-01-01
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Series: | Journal of Obesity & Metabolic Syndrome |
Subjects: | |
Online Access: | http://www.jomes.org/journal/view.html?doi=10.7570/jomes24031 |
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